Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCA3043Hexulose-6-phosphate synthase; Identified by similarity to GP:6899861; match to protein family HMM PF00215. (215 aa)    
Predicted Functional Partners:
MCA3044
SIS domain protein; Identified by match to protein family HMM PF01380.
 
 0.999
MCA3050
SIS domain protein; Identified by match to protein family HMM PF01380.
  
 0.985
MCA2738
Putative hexulose-6-phosphate synthase/SIS domain protein; Identified by similarity to GP:6899861; match to protein family HMM PF00215; match to protein family HMM PF01380.
 
 
0.944
rpiA
Ribose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
    
 0.904
rpe
Ribulose-phosphate 3-epimerase; Identified by similarity to SP:P32661; match to protein family HMM PF00834; match to protein family HMM TIGR01163; Belongs to the ribulose-phosphate 3-epimerase family.
     
 0.901
rpiB
Ribose 5-phosphate isomerase B; Identified by similarity to SP:P37351; match to protein family HMM PF02502; match to protein family HMM TIGR00689; match to protein family HMM TIGR01120.
     
  0.900
gnd
6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
     
  0.900
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
     
 0.768
tkt-1
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
     
 0.724
tkt-2
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
     
 0.715
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.