close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dsbBDisulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. (164 aa)    
Predicted Functional Partners:
dsbA
Thiol:disulfide interchange protein DsbA; Identified by similarity to SP:P32557; match to protein family HMM PF01323.
 
 
 0.930
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
       0.796
MCA3062
Putative hemY protein; Identified by similarity to SP:P09128; match to protein family HMM PF00515; match to protein family HMM PF07219.
 
     0.778
hemDX
uroporphyrinogen-III synthase/uroporphyrin-III C-methyltransferase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
     0.768
MCA3058
Conserved hypothetical protein; Identified by similarity to GP:17431649; match to protein family HMM PF07311.
       0.674
dsbC
Thiol:disulfide interchange protein DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.
  
 
 0.662
MCA1863
Putative regulator protein; Identified by similarity to SP:P42505; match to protein family HMM PF00816.
  
     0.478
MCA3056
Conserved hypothetical protein; Identified by similarity to OMNI:NTL03PA01076.
       0.454
MCA3057
Conserved hypothetical protein; Identified by similarity to SP:P76146; match to protein family HMM PF05249.
       0.454
moaD
Molybdopterin converting factor, subunit 1; Identified by similarity to SP:P30748; match to protein family HMM PF02597; match to protein family HMM TIGR01682; match to protein family HMM TIGR01687.
       0.440
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.