Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
minECell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. (93 aa)    
Predicted Functional Partners:
minD
Septum site-determining protein MinD; Identified by similarity to SP:P18197; match to protein family HMM PF01656; match to protein family HMM TIGR01968.
 
 
 0.997
minC
Septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.
 
  
 0.946
parC
DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
   
    0.884
MCA1054
Putative outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
  
    0.786
lepB
Signal peptidase I; Identified by similarity to SP:P00803; match to protein family HMM PF00717; match to protein family HMM TIGR02227; Belongs to the peptidase S26 family.
   
    0.758
MCA0496
Conserved hypothetical protein TIGR01777; Identified by similarity to OMNI:NTL03PA04657; match to protein family HMM PF07993; match to protein family HMM TIGR01777.
   
  
 0.707
MCA2243
Conserved hypothetical protein TIGR01777; Identified by similarity to OMNI:NTL03PA04657; match to protein family HMM TIGR01777.
   
  
 0.707
MCA3069
Conserved hypothetical protein.
       0.671
phoU2
Phosphate transport system protein PhoU; Plays a role in the regulation of phosphate uptake.
   
    0.625
MCA3065
Phosphatidylethanolamine N-methyltransferase; Identified by similarity to SP:Q05197.
 
    0.556
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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