node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MCA0860 | MCA2029 | MCA0860 | MCA2029 | Conserved hypothetical protein; Identified by similarity to OMNI:NTL03PA05280; match to protein family HMM PF04340. | Conserved domain protein. | 0.577 |
MCA0860 | MCA2772 | MCA0860 | MCA2772 | Conserved hypothetical protein; Identified by similarity to OMNI:NTL03PA05280; match to protein family HMM PF04340. | Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. | 0.623 |
MCA0860 | MCA3090 | MCA0860 | MCA3090 | Conserved hypothetical protein; Identified by similarity to OMNI:NTL03PA05280; match to protein family HMM PF04340. | Conserved domain protein; Identified by similarity to OMNI:NTL03PA05053; match to protein family HMM PF05036. | 0.710 |
MCA0860 | ftsL | MCA0860 | MCA2435 | Conserved hypothetical protein; Identified by similarity to OMNI:NTL03PA05280; match to protein family HMM PF04340. | Putative cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.472 |
MCA1672 | MCA3090 | MCA1672 | MCA3090 | Putative penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Conserved domain protein; Identified by similarity to OMNI:NTL03PA05053; match to protein family HMM PF05036. | 0.819 |
MCA1672 | ftsA | MCA1672 | MCA2424 | Putative penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | 0.472 |
MCA1672 | ftsI | MCA1672 | MCA2434 | Putative penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | 0.822 |
MCA1672 | ftsQ | MCA1672 | MCA2425 | Putative penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Putative cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.562 |
MCA1672 | ftsW | MCA1672 | MCA2430 | Putative penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.645 |
MCA2029 | MCA0860 | MCA2029 | MCA0860 | Conserved domain protein. | Conserved hypothetical protein; Identified by similarity to OMNI:NTL03PA05280; match to protein family HMM PF04340. | 0.577 |
MCA2029 | MCA3090 | MCA2029 | MCA3090 | Conserved domain protein. | Conserved domain protein; Identified by similarity to OMNI:NTL03PA05053; match to protein family HMM PF05036. | 0.600 |
MCA2029 | ftsL | MCA2029 | MCA2435 | Conserved domain protein. | Putative cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.404 |
MCA2772 | MCA0860 | MCA2772 | MCA0860 | Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. | Conserved hypothetical protein; Identified by similarity to OMNI:NTL03PA05280; match to protein family HMM PF04340. | 0.623 |
MCA2772 | MCA3090 | MCA2772 | MCA3090 | Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. | Conserved domain protein; Identified by similarity to OMNI:NTL03PA05053; match to protein family HMM PF05036. | 0.745 |
MCA2772 | ftsA | MCA2772 | MCA2424 | Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | 0.555 |
MCA2772 | ftsL | MCA2772 | MCA2435 | Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. | Putative cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.738 |
MCA2772 | ftsQ | MCA2772 | MCA2425 | Conserved hypothetical protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. | Putative cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.417 |
MCA3090 | MCA0860 | MCA3090 | MCA0860 | Conserved domain protein; Identified by similarity to OMNI:NTL03PA05053; match to protein family HMM PF05036. | Conserved hypothetical protein; Identified by similarity to OMNI:NTL03PA05280; match to protein family HMM PF04340. | 0.710 |
MCA3090 | MCA1672 | MCA3090 | MCA1672 | Conserved domain protein; Identified by similarity to OMNI:NTL03PA05053; match to protein family HMM PF05036. | Putative penicillin-binding protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.819 |
MCA3090 | MCA2029 | MCA3090 | MCA2029 | Conserved domain protein; Identified by similarity to OMNI:NTL03PA05053; match to protein family HMM PF05036. | Conserved domain protein. | 0.600 |