Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCA3111Conserved hypothetical protein; Identified by similarity to OMNI:NTL01SM02805. (147 aa)    
Predicted Functional Partners:
MCA3112
SPFH domain/Band 7 family; Identified by similarity to GP:9971722; match to protein family HMM PF01145.
 
 
 0.984
cobS
Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
   
    0.763
MCA2157
Putative ribonuclease BN; Identified by similarity to GP:17428575; match to protein family HMM PF03631; match to protein family HMM TIGR00765.
   
  
 0.634
nifH
Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.
      
 0.618
nifD
Nitrogenase molybdenum-iron protein alpha chain; Identified by similarity to SP:P06120; match to protein family HMM PF00148; match to protein family HMM TIGR01282; match to protein family HMM TIGR01862.
      
 0.618
MCA0299
Putative methanol dehydrogenase protein, large subunit; Identified by similarity to SP:P15279; match to protein family HMM PF01011.
     
 0.618
mxaF
Methanol dehydrogenase protein, large subunit; Identified by similarity to SP:P16027; match to protein family HMM PF01011.
     
 0.618
MCA2130
Conserved hypothetical protein; Identified by similarity to GP:3282847.
      
 0.618
fhs
Formate--tetrahydrofolate ligase; Identified by similarity to SP:P21164; match to protein family HMM PF01268; Belongs to the formate--tetrahydrofolate ligase family.
      
 0.618
mch
Putative n5,n10-methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT; Belongs to the MCH family.
      
 0.618
Your Current Organism:
Methylococcus capsulatus
NCBI taxonomy Id: 243233
Other names: M. capsulatus str. Bath, Methylococcus capsulatus ATCC 33009, Methylococcus capsulatus Bath, Methylococcus capsulatus MC, Methylococcus capsulatus NCIB 11132, Methylococcus capsulatus str. Bath
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