Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
actPCation/acetate symporter ActP; Transports acetate; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (549 aa)    
Predicted Functional Partners:
plu0073
Unnamed protein product; Highly similar to putative membrane protein YjcH of Escherichia coli.
 
  
 0.998
acs
Acetyl-coenzyme A synthetase (acetate--COA ligase) (acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
  
  
 0.826
prpE
Propionate--CoA ligase (Propionyl-CoA synthetase).
  
  
 0.606
fadB
Fatty oxidation complex alpha subunit [includes: enoyl-CoA hydratase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
  
  
 0.512
plu0070
Sulfatase domain-containing protein; Truncated gene. Similar to the N-terminal region of putative transposase.
       0.439
plu0071
Unnamed protein product; Some similarities with unknown protein. Putative transmembrane protein.
       0.439
plu3921
Uncharacterized protein; Truncated gene. Some similarities with polyketide synthase type I.
  
  
 0.428
pta
Phosphate acetyltransferase (phosphotransacetylase); Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
   
  
 0.421
aceB
Malate synthase A (MSA).
  
  
 0.406
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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