Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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gphPhosphoglycolate phosphatase (PGP); Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. (234 aa)    
Predicted Functional Partners:
rpe
Ribulose-phosphate 3-epimerase (pentose-5-phosphate 3-epimerase) (PPE) (R5P3E).
  
  
 0.930
plu2182
Unnamed protein product; Similar to indigoidine systhesis protein and phosphoglycolate phosphatase.
  
  
 
0.925
ghrA
Glyoxylate/hydroxypyruvate reductase A; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
    
 0.904
plu0950
FAD-binding PCMH-type domain-containing protein; Unnamed protein product; Some similarities with eugenol hydroxylase flavoprotein subunit.
    
 0.903
trpS
tryptophanyl-tRNA synthetase (tryptophan--tRNA ligase) (TRPRS); Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
  
  
 0.877
dam
DNA adenine methylase (Deoxyadenosyl-methyltransferase).
  
  
 0.667
damX
Putative membrane protein DamX, interferes with cell division; Non-essential cell division protein.
 
     0.606
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
  
    0.524
ubiG
Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
  
  
 0.514
hisI
phosphoribosyl-AMP cyclohydrolase (PRA-CH) / phosphoribosyl-ATP pyrophosphatase (PRA-PH); In the C-terminal section; belongs to the PRA-PH family.
  
  
 0.439
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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