STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
mrcAPenicillin-binding protein 1A (PBP-1a) (PBP1a) (penicillin-binding protein A) [Includes: Penicillin-insensitive transglycosylase (Peptidoglycan TGase); Penicillin-sensitive transpeptidase (DD-transpeptidase)]. (842 aa)    
Predicted Functional Partners:
pbpA
Penicillin-binding protein 2 (PBP-2); Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
  
 
 0.966
ftsI
Peptidoglycan synthetase ftsI precursor (penicillin-binding protein 3) (PBP-3); Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
  
 
 0.963
mrcB
Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
 
 
0.944
dacB
Penicillin-binding protein 4 precursor (PBP-4) [Includes: D-alanyl-D-alanine carboxypeptidase (DD-peptidase) (DD-carboxypeptidase); D-alanyl-D-alanine-endopeptidase (DD-endopeptidase)].
  
  
 0.938
mtgA
Monofunctional biosynthetic peptidoglycan transglycosylase (monofunctional TGase); Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.
 
 
0.937
dacA
Serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6); Penicillin-binding protein 5 precursor (D-alanyl-D-alanine carboxypeptidase fraction A) (DD-peptidase) (DD-caroboxypeptidase) (PBP-5); Belongs to the peptidase S11 family.
     
 0.922
dacC
Serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6); Penicillin-binding protein 6 precursor (D-alanyl-D-alanine carboxypeptidase fraction C) (DD-pept (DD-carboxypeptidase) (PBP-6)idase); Belongs to the peptidase S11 family.
     
 0.922
pbpC
Penicillin-binding protein 1C (PBP-1C).
  
  
0.919
plu4002
Unnamed protein product; Similar to putative glycosylase YraM of Escherichia coli.
  
 
 
 0.839
trmE
tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
      
 0.814
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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