| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| adiA | astA | plu3319 | plu3109 | Biodegradative arginine decarboxylase. | Arginine N-succinyltransferase (AOST); Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine. | 0.907 |
| adiA | plu0158 | plu3319 | plu0158 | Biodegradative arginine decarboxylase. | Unnamed protein product; Similar to L-arginine:lysine amidinotransferase and similar to L-arginine:glycine amidinotransferase. | 0.902 |
| adiA | speA | plu3319 | plu3681 | Biodegradative arginine decarboxylase. | Biosynthetic arginine decarboxylase (ADC); Catalyzes the biosynthesis of agmatine from arginine. | 0.918 |
| aldB | plu0142 | plu3739 | plu0142 | Aldehyde dehydrogenase B (Lactaldehyde dehydrogenase); Belongs to the aldehyde dehydrogenase family. | Aldedh domain-containing protein; Unnamed protein product; Similar to NADP-dependent aldehyde dehydrogenase. | 0.906 |
| aldB | plu0158 | plu3739 | plu0158 | Aldehyde dehydrogenase B (Lactaldehyde dehydrogenase); Belongs to the aldehyde dehydrogenase family. | Unnamed protein product; Similar to L-arginine:lysine amidinotransferase and similar to L-arginine:glycine amidinotransferase. | 0.900 |
| astA | adiA | plu3109 | plu3319 | Arginine N-succinyltransferase (AOST); Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine. | Biodegradative arginine decarboxylase. | 0.907 |
| astA | plu0158 | plu3109 | plu0158 | Arginine N-succinyltransferase (AOST); Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine. | Unnamed protein product; Similar to L-arginine:lysine amidinotransferase and similar to L-arginine:glycine amidinotransferase. | 0.900 |
| astA | speA | plu3109 | plu3681 | Arginine N-succinyltransferase (AOST); Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine. | Biosynthetic arginine decarboxylase (ADC); Catalyzes the biosynthesis of agmatine from arginine. | 0.912 |
| gcvP | glyA | plu3596 | plu3291 | Glycine dehydrogenase [decarboxylating] (glycine decarboxylase) (glycine cleavage system P-protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Serine hydroxymethyltransferase (serine methylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.995 |
| gcvP | kbl | plu3596 | plu4846 | Glycine dehydrogenase [decarboxylating] (glycine decarboxylase) (glycine cleavage system P-protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 2-amino-3-ketobutyrate coenzyme A ligase (AKB ligase) (glycine acetyltransferase); Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.938 |
| gcvP | plu0158 | plu3596 | plu0158 | Glycine dehydrogenase [decarboxylating] (glycine decarboxylase) (glycine cleavage system P-protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Unnamed protein product; Similar to L-arginine:lysine amidinotransferase and similar to L-arginine:glycine amidinotransferase. | 0.900 |
| gcvP | plu4266 | plu3596 | plu4266 | Glycine dehydrogenase [decarboxylating] (glycine decarboxylase) (glycine cleavage system P-protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | DAO domain-containing protein; Unnamed protein product; Some similarities with sarcosine oxidase. | 0.917 |
| glyA | gcvP | plu3291 | plu3596 | Serine hydroxymethyltransferase (serine methylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Glycine dehydrogenase [decarboxylating] (glycine decarboxylase) (glycine cleavage system P-protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.995 |
| glyA | kbl | plu3291 | plu4846 | Serine hydroxymethyltransferase (serine methylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 2-amino-3-ketobutyrate coenzyme A ligase (AKB ligase) (glycine acetyltransferase); Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.910 |
| glyA | plu0158 | plu3291 | plu0158 | Serine hydroxymethyltransferase (serine methylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Unnamed protein product; Similar to L-arginine:lysine amidinotransferase and similar to L-arginine:glycine amidinotransferase. | 0.900 |
| glyA | plu4266 | plu3291 | plu4266 | Serine hydroxymethyltransferase (serine methylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | DAO domain-containing protein; Unnamed protein product; Some similarities with sarcosine oxidase. | 0.909 |
| kbl | gcvP | plu4846 | plu3596 | 2-amino-3-ketobutyrate coenzyme A ligase (AKB ligase) (glycine acetyltransferase); Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | Glycine dehydrogenase [decarboxylating] (glycine decarboxylase) (glycine cleavage system P-protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.938 |
| kbl | glyA | plu4846 | plu3291 | 2-amino-3-ketobutyrate coenzyme A ligase (AKB ligase) (glycine acetyltransferase); Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | Serine hydroxymethyltransferase (serine methylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.910 |
| kbl | plu0158 | plu4846 | plu0158 | 2-amino-3-ketobutyrate coenzyme A ligase (AKB ligase) (glycine acetyltransferase); Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | Unnamed protein product; Similar to L-arginine:lysine amidinotransferase and similar to L-arginine:glycine amidinotransferase. | 0.900 |
| kbl | plu4266 | plu4846 | plu4266 | 2-amino-3-ketobutyrate coenzyme A ligase (AKB ligase) (glycine acetyltransferase); Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | DAO domain-containing protein; Unnamed protein product; Some similarities with sarcosine oxidase. | 0.901 |
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