Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
uxuAMannonate dehydratase (D-mannonate hydrolase); Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family. (395 aa)    
Predicted Functional Partners:
uxuB
D-mannonate oxidoreductase (fructuronate reductase); Belongs to the mannitol dehydrogenase family.
 
 
 0.987
uxaC
Uronate isomerase (glucuronate isomerase) (uronic isomerase).
 
  
 0.968
kdgK
2-dehydro-3-deoxygluconokinase (2-keto-3-deoxygluconokinase) (3-deoxy-2-OXO-D-gluconate kinase) (KDG kinase).
 
  
 0.935
rpiA
Ribose 5-phosphate isomerase A (phosphoriboisomerase A); Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
     
 0.816
uxuR
Uxu operon transcriptional regulator.
 
   
 0.814
rpe
Ribulose-phosphate 3-epimerase (pentose-5-phosphate 3-epimerase) (PPE) (R5P3E).
     
 0.806
gnd
6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
     
  0.800
plu0172
Unnamed protein product; Similar to dicarboxylate-binding periplasmic protein and to unknown protein YiaO of Escherichia coli.
 
   
 0.747
plu0173
Unnamed protein product; Similar to dicarboxylate transport system (permease small protein) and to unknown protein YiaM of Escherichia coli.
 
     0.640
plu0174
DctM domain-containing protein; Unnamed protein product; Similar to dicarboxylate transport system (permease large protein) and to unknown protein YiaN of Escherichia coli.
 
  
 0.628
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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