Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cpmACpmA protein involved in carbapenem biosynthesis. (501 aa)    
Predicted Functional Partners:
cpmB
CpmB protein involved in carbapenem biosynthesis.
   
 0.976
cpmC
CpmC protein involved in carbapenem biosynthesis.
 
 
  0.914
cpmD
CpmD protein involved in carbapenem biosynthesis.
     
 0.902
cpmE
CpmE protein involved in carbapenem biosynthesis.
   
 
  0.900
plu2670
Unnamed protein product; Similar to proteins involved in antibiotic biosynthesis (tyrocidin, gramicidin, surfactin, pyoverdine). Putative transmembrane protein.
 
  
 0.674
gltB
Glutamate synthase [NADPH] large chain precursor (glutamate synthase alpha subunit) (NADPH-GOGAT) (GLTS alpha chain).
  
  
 0.670
slyA
Transcriptional regulator protein SlyA; Transcription regulator that can specifically activate or repress expression of target genes. Regulates the cpm operon, which contains cpmA, cpmB, cpmC, cpmD, cpmE, cpmF, cpmG and cpmH, involved in carbapenem-like antibiotic production; Belongs to the SlyA family.
     
 0.629
cpmH
CpmH protein, probably involved in carbapenem biosynthesis or resistance.
      
 0.623
plu2321
Unnamed protein product; Similar to protein HMWP1 of Yersinia enterocolitica.
  
 
 0.563
plu1880
Unnamed protein product; Similar to proteins involved in antibiotic biosynthesis. Putative transmembrane protein.
 
 
 0.548
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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