STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cpmHCpmH protein, probably involved in carbapenem biosynthesis or resistance. (181 aa)    
Predicted Functional Partners:
cpmA
CpmA protein involved in carbapenem biosynthesis.
      
 0.623
slyA
Transcriptional regulator protein SlyA; Transcription regulator that can specifically activate or repress expression of target genes. Regulates the cpm operon, which contains cpmA, cpmB, cpmC, cpmD, cpmE, cpmF, cpmG and cpmH, involved in carbapenem-like antibiotic production; Belongs to the SlyA family.
      
 0.623
plu2670
Unnamed protein product; Similar to proteins involved in antibiotic biosynthesis (tyrocidin, gramicidin, surfactin, pyoverdine). Putative transmembrane protein.
      
 0.540
plu4186
Unnamed protein product; Weakly similar to unknown protein; Belongs to the UPF0255 family.
      
 0.540
luxS
Autoinducer-2 (AI-2) production protein LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
      
 0.539
plu4194
Unnamed protein product; Similar to polyketide ketoreductase.
      
 0.539
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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