Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
glpRGlycerol-3-phosphate regulon repressor. (252 aa)    
Predicted Functional Partners:
glpD
Aerobic glycerol-3-phosphate dehydrogenase GlpD; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
 
  
 0.826
glpG
Protein GlpG; Rhomboid-type serine protease that catalyzes intramembrane proteolysis.
     
 0.799
glpE
Thiosulfate sulfurtransferase GlpE; Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
       0.790
fruA
PTS system, fructose-specific IIBC component.
 
  
 0.762
fruK
1-phosphofructokinase (fructose 1-phosphate kinase); Belongs to the carbohydrate kinase PfkB family.
 
  
 0.668
mutL
DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
   
  
 0.603
plu1878
Carrier domain-containing protein; Unnamed protein product; Similar to antibiotic synthetase.
     
 0.546
plu1880
Unnamed protein product; Similar to proteins involved in antibiotic biosynthesis. Putative transmembrane protein.
     
 0.542
plu1881
Unnamed protein product; Weakly similar to unknown protein.
      
 0.540
nfuA
Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
     
 0.537
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.