Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ompRTwo-component response regulator. (239 aa)    
Predicted Functional Partners:
envZ
Osmolarity sensor protein.
 
 0.995
arcB
Aerobic respiration control sensor protein.
 
 
 0.974
barA
Sensor protein BarA.
 
 
 0.944
bvgS
Virulence sensor protein BvgS precursor.
 
 
 0.910
cpxA
Two-component sensor kinase.
 
 
 0.898
phoR
Phosphate regulon sensor protein.
 
 
 0.824
phoQ
Two-component sensor kinase PhoQ.
 
 
 0.811
nuoC
NADH dehydrogenase I chain C/D (NADH-ubiquinone oxidoreductase chain 3/4) (NUO3/NUO4); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
  
   0.702
uvrY
Transcription regulator.
  
 
 
 0.695
slyA
Transcriptional regulator protein SlyA; Transcription regulator that can specifically activate or repress expression of target genes. Regulates the cpm operon, which contains cpmA, cpmB, cpmC, cpmD, cpmE, cpmF, cpmG and cpmH, involved in carbapenem-like antibiotic production; Belongs to the SlyA family.
      
 0.663
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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