| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| arcA | bvgS | plu0562 | plu2284 | Two-component system, OmpR family, aerobic respiration control protein ArcA; Negative response regulator of genes in aerobic pathways, (sensors, ArcB and CpxA) (dye resistance protein). | Virulence sensor protein BvgS precursor. | 0.939 |
| arcA | envZ | plu0562 | plu0213 | Two-component system, OmpR family, aerobic respiration control protein ArcA; Negative response regulator of genes in aerobic pathways, (sensors, ArcB and CpxA) (dye resistance protein). | Osmolarity sensor protein. | 0.811 |
| arcA | rcsD | plu0562 | plu3047 | Two-component system, OmpR family, aerobic respiration control protein ArcA; Negative response regulator of genes in aerobic pathways, (sensors, ArcB and CpxA) (dye resistance protein). | Phosphotransferase RcsD; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB. | 0.655 |
| baeR | bvgS | plu2778 | plu2284 | Two-component response regulator. | Virulence sensor protein BvgS precursor. | 0.950 |
| baeR | envZ | plu2778 | plu0213 | Two-component response regulator. | Osmolarity sensor protein. | 0.729 |
| baeR | rcsD | plu2778 | plu3047 | Two-component response regulator. | Phosphotransferase RcsD; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB. | 0.726 |
| bvgS | arcA | plu2284 | plu0562 | Virulence sensor protein BvgS precursor. | Two-component system, OmpR family, aerobic respiration control protein ArcA; Negative response regulator of genes in aerobic pathways, (sensors, ArcB and CpxA) (dye resistance protein). | 0.939 |
| bvgS | baeR | plu2284 | plu2778 | Virulence sensor protein BvgS precursor. | Two-component response regulator. | 0.950 |
| bvgS | cpxR | plu2284 | plu4794 | Virulence sensor protein BvgS precursor. | Two-component response regulator. | 0.930 |
| bvgS | envZ | plu2284 | plu0213 | Virulence sensor protein BvgS precursor. | Osmolarity sensor protein. | 0.744 |
| bvgS | ompR | plu2284 | plu0212 | Virulence sensor protein BvgS precursor. | Two-component response regulator. | 0.949 |
| bvgS | phoB | plu2284 | plu3911 | Virulence sensor protein BvgS precursor. | Phosphate regulon transcriptional regulatory protein. | 0.924 |
| bvgS | phoP | plu2284 | plu2807 | Virulence sensor protein BvgS precursor. | Two-component response regulator PhoP. | 0.945 |
| bvgS | rcsD | plu2284 | plu3047 | Virulence sensor protein BvgS precursor. | Phosphotransferase RcsD; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB. | 0.940 |
| cpxR | bvgS | plu4794 | plu2284 | Two-component response regulator. | Virulence sensor protein BvgS precursor. | 0.930 |
| cpxR | envZ | plu4794 | plu0213 | Two-component response regulator. | Osmolarity sensor protein. | 0.799 |
| cpxR | rcsD | plu4794 | plu3047 | Two-component response regulator. | Phosphotransferase RcsD; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB. | 0.709 |
| envZ | arcA | plu0213 | plu0562 | Osmolarity sensor protein. | Two-component system, OmpR family, aerobic respiration control protein ArcA; Negative response regulator of genes in aerobic pathways, (sensors, ArcB and CpxA) (dye resistance protein). | 0.811 |
| envZ | baeR | plu0213 | plu2778 | Osmolarity sensor protein. | Two-component response regulator. | 0.729 |
| envZ | bvgS | plu0213 | plu2284 | Osmolarity sensor protein. | Virulence sensor protein BvgS precursor. | 0.744 |