| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| bvgS | phoB | plu2284 | plu3911 | Virulence sensor protein BvgS precursor. | Phosphate regulon transcriptional regulatory protein. | 0.865 |
| bvgS | phoR | plu2284 | plu3910 | Virulence sensor protein BvgS precursor. | Phosphate regulon sensor protein. | 0.729 |
| bvgS | phoU | plu2284 | plu0218 | Virulence sensor protein BvgS precursor. | Phosphate transport system protein PhoU; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. | 0.583 |
| bvgS | pstA | plu2284 | plu0216 | Virulence sensor protein BvgS precursor. | Phosphate transport system permease protein PstA. | 0.446 |
| bvgS | pstB | plu2284 | plu0217 | Virulence sensor protein BvgS precursor. | Phosphate transport system permease protein PstB; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. | 0.505 |
| bvgS | pstS | plu2284 | plu0214 | Virulence sensor protein BvgS precursor. | Phosphate-binding periplasmic protein precursor PstS; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family. | 0.612 |
| bvgS | rpoN | plu2284 | plu4041 | Virulence sensor protein BvgS precursor. | RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.581 |
| minE | parC | plu2136 | plu3949 | Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | Topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | 0.923 |
| minE | phoU | plu2136 | plu0218 | Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | Phosphate transport system protein PhoU; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. | 0.570 |
| minE | rpoN | plu2136 | plu4041 | Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.514 |
| parC | minE | plu3949 | plu2136 | Topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.923 |
| parC | phoU | plu3949 | plu0218 | Topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | Phosphate transport system protein PhoU; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. | 0.677 |
| parC | rpoN | plu3949 | plu4041 | Topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.552 |
| phoB | bvgS | plu3911 | plu2284 | Phosphate regulon transcriptional regulatory protein. | Virulence sensor protein BvgS precursor. | 0.865 |
| phoB | phoR | plu3911 | plu3910 | Phosphate regulon transcriptional regulatory protein. | Phosphate regulon sensor protein. | 0.999 |
| phoB | phoU | plu3911 | plu0218 | Phosphate regulon transcriptional regulatory protein. | Phosphate transport system protein PhoU; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. | 0.553 |
| phoB | pstB | plu3911 | plu0217 | Phosphate regulon transcriptional regulatory protein. | Phosphate transport system permease protein PstB; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. | 0.426 |
| phoB | pstS | plu3911 | plu0214 | Phosphate regulon transcriptional regulatory protein. | Phosphate-binding periplasmic protein precursor PstS; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family. | 0.538 |
| phoR | bvgS | plu3910 | plu2284 | Phosphate regulon sensor protein. | Virulence sensor protein BvgS precursor. | 0.729 |
| phoR | phoB | plu3910 | plu3911 | Phosphate regulon sensor protein. | Phosphate regulon transcriptional regulatory protein. | 0.999 |