| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| bvgS | phoB | plu2284 | plu3911 | Virulence sensor protein BvgS precursor. | Phosphate regulon transcriptional regulatory protein. | 0.924 |
| bvgS | phoR | plu2284 | plu3910 | Virulence sensor protein BvgS precursor. | Phosphate regulon sensor protein. | 0.641 |
| bvgS | phoU | plu2284 | plu0218 | Virulence sensor protein BvgS precursor. | Phosphate transport system protein PhoU; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. | 0.464 |
| bvgS | pstA | plu2284 | plu0216 | Virulence sensor protein BvgS precursor. | Phosphate transport system permease protein PstA. | 0.478 |
| bvgS | pstB | plu2284 | plu0217 | Virulence sensor protein BvgS precursor. | Phosphate transport system permease protein PstB; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. | 0.481 |
| bvgS | pstS | plu2284 | plu0214 | Virulence sensor protein BvgS precursor. | Phosphate-binding periplasmic protein precursor PstS; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family. | 0.478 |
| bvgS | rpoN | plu2284 | plu4041 | Virulence sensor protein BvgS precursor. | RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.476 |
| parC | phoU | plu3949 | plu0218 | Topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | Phosphate transport system protein PhoU; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. | 0.559 |
| parC | rpoN | plu3949 | plu4041 | Topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.449 |
| phoB | bvgS | plu3911 | plu2284 | Phosphate regulon transcriptional regulatory protein. | Virulence sensor protein BvgS precursor. | 0.924 |
| phoB | phoR | plu3911 | plu3910 | Phosphate regulon transcriptional regulatory protein. | Phosphate regulon sensor protein. | 0.998 |
| phoB | phoU | plu3911 | plu0218 | Phosphate regulon transcriptional regulatory protein. | Phosphate transport system protein PhoU; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. | 0.492 |
| phoR | bvgS | plu3910 | plu2284 | Phosphate regulon sensor protein. | Virulence sensor protein BvgS precursor. | 0.641 |
| phoR | phoB | plu3910 | plu3911 | Phosphate regulon sensor protein. | Phosphate regulon transcriptional regulatory protein. | 0.998 |
| phoR | phoU | plu3910 | plu0218 | Phosphate regulon sensor protein. | Phosphate transport system protein PhoU; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. | 0.564 |
| phoR | pstB | plu3910 | plu0217 | Phosphate regulon sensor protein. | Phosphate transport system permease protein PstB; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. | 0.465 |
| phoR | pstS | plu3910 | plu0214 | Phosphate regulon sensor protein. | Phosphate-binding periplasmic protein precursor PstS; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family. | 0.427 |
| phoU | bvgS | plu0218 | plu2284 | Phosphate transport system protein PhoU; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. | Virulence sensor protein BvgS precursor. | 0.464 |
| phoU | parC | plu0218 | plu3949 | Phosphate transport system protein PhoU; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. | Topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | 0.559 |
| phoU | phoB | plu0218 | plu3911 | Phosphate transport system protein PhoU; Part of the phosphate (Pho) regulon, which plays a key role in phosphate homeostasis. PhoU is essential for the repression of the Pho regulon at high phosphate conditions. | Phosphate regulon transcriptional regulatory protein. | 0.492 |