| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| bvgS | fnr | plu2284 | plu2179 | Virulence sensor protein BvgS precursor. | Fumarate and nitrate reduction regulatory protein. | 0.558 |
| bvgS | hemN | plu2284 | plu0230 | Virulence sensor protein BvgS precursor. | Oxygen-independent coproporphyrinogen III oxidase (coproporphyrinogenase) (coprogen oxidase); Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.478 |
| fnr | bvgS | plu2179 | plu2284 | Fumarate and nitrate reduction regulatory protein. | Virulence sensor protein BvgS precursor. | 0.558 |
| fnr | hemN | plu2179 | plu0230 | Fumarate and nitrate reduction regulatory protein. | Oxygen-independent coproporphyrinogen III oxidase (coproporphyrinogenase) (coprogen oxidase); Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.633 |
| fnr | ompW | plu2179 | plu2478 | Fumarate and nitrate reduction regulatory protein. | Outer membrane protein W precursor; Truncated gene. Some similarities with truncated transposase, IS4 family of Photorhabdus. | 0.475 |
| hemC | hemE | plu4644 | plu0489 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.985 |
| hemC | hemF | plu4644 | plu1383 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Oxygen-dependent coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.531 |
| hemC | hemN | plu4644 | plu0230 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Oxygen-independent coproporphyrinogen III oxidase (coproporphyrinogenase) (coprogen oxidase); Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.490 |
| hemE | hemC | plu0489 | plu4644 | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.985 |
| hemE | hemF | plu0489 | plu1383 | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | Oxygen-dependent coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.960 |
| hemE | hemN | plu0489 | plu0230 | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | Oxygen-independent coproporphyrinogen III oxidase (coproporphyrinogenase) (coprogen oxidase); Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.963 |
| hemF | hemC | plu1383 | plu4644 | Oxygen-dependent coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.531 |
| hemF | hemE | plu1383 | plu0489 | Oxygen-dependent coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.960 |
| hemF | hemG | plu1383 | plu4398 | Oxygen-dependent coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Protoporphyrinogen oxidase (PPO). | 0.927 |
| hemF | hemN | plu1383 | plu0230 | Oxygen-dependent coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Oxygen-independent coproporphyrinogen III oxidase (coproporphyrinogenase) (coprogen oxidase); Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.935 |
| hemG | hemF | plu4398 | plu1383 | Protoporphyrinogen oxidase (PPO). | Oxygen-dependent coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.927 |
| hemG | hemN | plu4398 | plu0230 | Protoporphyrinogen oxidase (PPO). | Oxygen-independent coproporphyrinogen III oxidase (coproporphyrinogenase) (coprogen oxidase); Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.919 |
| hemN | bvgS | plu0230 | plu2284 | Oxygen-independent coproporphyrinogen III oxidase (coproporphyrinogenase) (coprogen oxidase); Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Virulence sensor protein BvgS precursor. | 0.478 |
| hemN | fnr | plu0230 | plu2179 | Oxygen-independent coproporphyrinogen III oxidase (coproporphyrinogenase) (coprogen oxidase); Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Fumarate and nitrate reduction regulatory protein. | 0.633 |
| hemN | hemC | plu0230 | plu4644 | Oxygen-independent coproporphyrinogen III oxidase (coproporphyrinogenase) (coprogen oxidase); Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.490 |