Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
plu0449CTP_transf_like domain-containing protein; Unnamed protein product; Some similarities with unknown protein. (208 aa)    
Predicted Functional Partners:
plu0451
Unnamed protein product; Similar to unknown protein.
 
    0.825
plu0450
Unnamed protein product; Unknown protein.
       0.779
pdl
Pdl protein; Similar to putative lipase of Photorhabdus luminescens, strain W14.
  
     0.609
plu4537
CRM domain-containing protein; Unnamed protein product; Highly similar to unknown protein YhbY of Escherichia coli.
  
  
 0.570
ribD
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.560
rsfS
Ribosomal silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
  
  
 0.545
plu0936
Thymidylate_kin domain-containing protein; Unnamed protein product; Some similarities with thymidylate kinase.
  
     0.540
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
  
 0.534
plu0930
Fe2OG dioxygenase domain-containing protein; Unnamed protein product; Highly similar to unknown protein of Photorhabdus and some weak similarities with dioxygenase; Belongs to the iron/ascorbate-dependent oxidoreductase family.
  
     0.525
cdd
Cytidine deaminase (Cytidine aminohydrolase) (CDA); This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
  
     0.498
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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