| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cpxA | cyaA | plu4795 | plu4643 | Two-component sensor kinase. | Adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase); Belongs to the adenylyl cyclase class-1 family. | 0.669 |
| cpxA | glnE | plu4795 | plu3969 | Two-component sensor kinase. | Glutamate-ammonia-ligase adenylyltransferase (glutamine-synthetase adenylyltransferase) (ATASE); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. Th [...] | 0.548 |
| cpxA | malF | plu4795 | plu0459 | Two-component sensor kinase. | Maltose transport inner membrane protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane. | 0.570 |
| cyaA | cpxA | plu4643 | plu4795 | Adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase); Belongs to the adenylyl cyclase class-1 family. | Two-component sensor kinase. | 0.669 |
| cyaA | glnE | plu4643 | plu3969 | Adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase); Belongs to the adenylyl cyclase class-1 family. | Glutamate-ammonia-ligase adenylyltransferase (glutamine-synthetase adenylyltransferase) (ATASE); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. Th [...] | 0.540 |
| cyaA | malF | plu4643 | plu0459 | Adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase); Belongs to the adenylyl cyclase class-1 family. | Maltose transport inner membrane protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane. | 0.593 |
| glnE | cpxA | plu3969 | plu4795 | Glutamate-ammonia-ligase adenylyltransferase (glutamine-synthetase adenylyltransferase) (ATASE); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. Th [...] | Two-component sensor kinase. | 0.548 |
| glnE | cyaA | plu3969 | plu4643 | Glutamate-ammonia-ligase adenylyltransferase (glutamine-synthetase adenylyltransferase) (ATASE); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. Th [...] | Adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase); Belongs to the adenylyl cyclase class-1 family. | 0.540 |
| glnE | malF | plu3969 | plu0459 | Glutamate-ammonia-ligase adenylyltransferase (glutamine-synthetase adenylyltransferase) (ATASE); Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. Th [...] | Maltose transport inner membrane protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane. | 0.600 |
| lamB | malE | plu0456 | plu0458 | Maltoporin precursor (Maltose-inducible porin) (Lambda receptor protein); Involved in the transport of maltose and maltodextrins. Belongs to the porin LamB (TC 1.B.3) family. | Periplasmic maltose-binding protein precursor; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins. Belongs to the bacterial solute-binding protein 1 family. | 0.952 |
| lamB | malF | plu0456 | plu0459 | Maltoporin precursor (Maltose-inducible porin) (Lambda receptor protein); Involved in the transport of maltose and maltodextrins. Belongs to the porin LamB (TC 1.B.3) family. | Maltose transport inner membrane protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane. | 0.894 |
| lamB | malG | plu0456 | plu0460 | Maltoporin precursor (Maltose-inducible porin) (Lambda receptor protein); Involved in the transport of maltose and maltodextrins. Belongs to the porin LamB (TC 1.B.3) family. | Maltose transport inner membrane protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane. | 0.906 |
| lamB | malK | plu0456 | plu0457 | Maltoporin precursor (Maltose-inducible porin) (Lambda receptor protein); Involved in the transport of maltose and maltodextrins. Belongs to the porin LamB (TC 1.B.3) family. | Maltose/maltodextrin transport ATP-binding protein MalK; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family. | 0.940 |
| lamB | malM | plu0456 | plu0455 | Maltoporin precursor (Maltose-inducible porin) (Lambda receptor protein); Involved in the transport of maltose and maltodextrins. Belongs to the porin LamB (TC 1.B.3) family. | Maltose operon periplasmic protein. | 0.973 |
| lamB | malT | plu0456 | plu0471 | Maltoporin precursor (Maltose-inducible porin) (Lambda receptor protein); Involved in the transport of maltose and maltodextrins. Belongs to the porin LamB (TC 1.B.3) family. | Positive regulator of mal regulon; Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto- oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box. | 0.753 |
| malE | lamB | plu0458 | plu0456 | Periplasmic maltose-binding protein precursor; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins. Belongs to the bacterial solute-binding protein 1 family. | Maltoporin precursor (Maltose-inducible porin) (Lambda receptor protein); Involved in the transport of maltose and maltodextrins. Belongs to the porin LamB (TC 1.B.3) family. | 0.952 |
| malE | malF | plu0458 | plu0459 | Periplasmic maltose-binding protein precursor; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins. Belongs to the bacterial solute-binding protein 1 family. | Maltose transport inner membrane protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane. | 0.999 |
| malE | malG | plu0458 | plu0460 | Periplasmic maltose-binding protein precursor; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins. Belongs to the bacterial solute-binding protein 1 family. | Maltose transport inner membrane protein; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane. | 0.999 |
| malE | malK | plu0458 | plu0457 | Periplasmic maltose-binding protein precursor; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins. Belongs to the bacterial solute-binding protein 1 family. | Maltose/maltodextrin transport ATP-binding protein MalK; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family. | 0.998 |
| malE | malM | plu0458 | plu0455 | Periplasmic maltose-binding protein precursor; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins. Belongs to the bacterial solute-binding protein 1 family. | Maltose operon periplasmic protein. | 0.972 |