thiC protein (Photorhabdus laumondii) - STRING interaction network

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thiC

Thiamin biosynthesis protein thiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (645 aa)

Predicted Functional Partners:

thiG

0.990

thiD

0.989

thiE

0.983

thiS

0.964

thiH

0.957

thiF

0.922

purM

0.808

purK

0.800

plu3918

0.732

plu1515

0.669

Your Current Organism:

Photorhabdus laumondii

NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
plu1515	thiC	plu1515	plu0486	ThiF domain-containing protein; Unnamed protein product; Similar to MccB protein of Escherichia coli, involved in the production of microcin C7.	Thiamin biosynthesis protein thiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	0.669
plu1515	thiD	plu1515	plu2782	ThiF domain-containing protein; Unnamed protein product; Similar to MccB protein of Escherichia coli, involved in the production of microcin C7.	Phosphomethylpyrimidine kinase (HMP-phosphate kinase).	0.573
plu1515	thiE	plu1515	plu0485	ThiF domain-containing protein; Unnamed protein product; Similar to MccB protein of Escherichia coli, involved in the production of microcin C7.	Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	0.734
plu1515	thiG	plu1515	plu0482	ThiF domain-containing protein; Unnamed protein product; Similar to MccB protein of Escherichia coli, involved in the production of microcin C7.	Thiamin biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.	0.815
plu1515	thiH	plu1515	plu0481	ThiF domain-containing protein; Unnamed protein product; Similar to MccB protein of Escherichia coli, involved in the production of microcin C7.	Thiamin biosynthesis, thiazole moiety.	0.761
plu1515	thiS	plu1515	plu0483	ThiF domain-containing protein; Unnamed protein product; Similar to MccB protein of Escherichia coli, involved in the production of microcin C7.	ThiS protein.	0.810
plu3918	thiC	plu3918	plu0486	Unnamed protein product; Hypothetical protein.	Thiamin biosynthesis protein thiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	0.732
plu3918	thiE	plu3918	plu0485	Unnamed protein product; Hypothetical protein.	Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	0.729
plu3918	thiG	plu3918	plu0482	Unnamed protein product; Hypothetical protein.	Thiamin biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.	0.784
plu3918	thiS	plu3918	plu0483	Unnamed protein product; Hypothetical protein.	ThiS protein.	0.668
purK	purM	plu3808	plu2760	Phosphoribosylaminoimidazole carboxylase ATPase subunit (AIR carboxylase) (AIRC); Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).	Phosphoribosylformylglycinamidine cyclo-ligase (AIRS) (phosphoribosyl-aminoimidazole synthetase) (AIR synthase).	0.996
purK	thiC	plu3808	plu0486	Phosphoribosylaminoimidazole carboxylase ATPase subunit (AIR carboxylase) (AIRC); Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).	Thiamin biosynthesis protein thiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	0.800
purM	purK	plu2760	plu3808	Phosphoribosylformylglycinamidine cyclo-ligase (AIRS) (phosphoribosyl-aminoimidazole synthetase) (AIR synthase).	Phosphoribosylaminoimidazole carboxylase ATPase subunit (AIR carboxylase) (AIRC); Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).	0.996
purM	thiC	plu2760	plu0486	Phosphoribosylformylglycinamidine cyclo-ligase (AIRS) (phosphoribosyl-aminoimidazole synthetase) (AIR synthase).	Thiamin biosynthesis protein thiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	0.808
thiC	plu1515	plu0486	plu1515	Thiamin biosynthesis protein thiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	ThiF domain-containing protein; Unnamed protein product; Similar to MccB protein of Escherichia coli, involved in the production of microcin C7.	0.669
thiC	plu3918	plu0486	plu3918	Thiamin biosynthesis protein thiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	Unnamed protein product; Hypothetical protein.	0.732
thiC	purK	plu0486	plu3808	Thiamin biosynthesis protein thiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	Phosphoribosylaminoimidazole carboxylase ATPase subunit (AIR carboxylase) (AIRC); Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).	0.800
thiC	purM	plu0486	plu2760	Thiamin biosynthesis protein thiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	Phosphoribosylformylglycinamidine cyclo-ligase (AIRS) (phosphoribosyl-aminoimidazole synthetase) (AIR synthase).	0.808
thiC	thiD	plu0486	plu2782	Thiamin biosynthesis protein thiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	Phosphomethylpyrimidine kinase (HMP-phosphate kinase).	0.989
thiC	thiE	plu0486	plu0485	Thiamin biosynthesis protein thiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.	Thiamin-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.	0.983

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