Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
deoDPurine-nucleoside phosphorylase (inosine phosphorylase) (PNP). (238 aa)    
Predicted Functional Partners:
deoB
Phosphopentomutase (phosphodeoxyribomutase); Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
 
 
 0.975
nadR
Transcriptional regulator NadR.
    
 0.933
gpt
Xanthine-guanine phosphoribosyltransferase (XGPRT); Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
    
 0.926
ushA
Protein UshA precursor [Includes: UDP-sugar hydrolase (UDP-sugar diphosphatase) (UDP-sugar pyrophosphatase); 5'-nucleotidase (5'-NT)]; Belongs to the 5'-nucleotidase family.
    
 0.915
apt
Adenine phosphoribosyltransferase (APRT); Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
 0.915
pcnB-2
Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
     
 0.914
add
Adenosine deaminase (adenosine aminohydrolase); Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
    
 0.914
plu2772
A_deaminase domain-containing protein; Unnamed protein product; Similar to adenosine deaminase.
    
 0.914
cobB
CobB protein; Belongs to the sirtuin family. Class III subfamily.
    
 0.913
plu0860
Unnamed protein product; Highly similar to hypoxanthine phosphoribosyltransferase of Escherichia coli; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
 0.905
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.