Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (309 aa)    
Predicted Functional Partners:
thrA
Aspartokinase I-homoserine dehydrogenase I; In the C-terminal section; belongs to the homoserine dehydrogenase family.
 
 0.999
thrC
Threonine synthase.
 
 0.999
metL
Bifunctional aspartokinase/homoserine dehydrogenase II (AKII-HDII) [Includes: Aspartokinase II; homoserine dehydrogenase II]; In the C-terminal section; belongs to the homoserine dehydrogenase family.
 
 0.998
metA
Homoserine O-succinyltransferase (homoserine O-transsuccinylase) (HTS); Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.
    
 0.917
lysC
Lysine-sensitive aspartokinase III (aspartate kinase III); Belongs to the aspartokinase family.
 
 
 0.840
plu0523
Unnamed protein product; Similar to cystathionine gamma-lyase.
  
 
 0.835
metB
Cystathionine gamma-synthase (CGS) (O-succinylhomoserine (Thiol)-lyase).
  
 
 0.835
sdaA
L-serine dehydratase 1 (SDH 1); Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
 
 0.834
metC
Cystathionine beta-lyase (CHL) (beta-cystathionase) (cysteine lyase).
  
 
 0.833
plu1438
Unnamed protein product; Similar to branched-chain amino acid aminotransferases.
  
 
 0.824
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.