Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
plu0664DUF446 domain-containing protein; Unnamed protein product; Similar to unknown protein YqcC of Escherichia coli. (110 aa)    
Predicted Functional Partners:
sdhC
Succinate dehydrogenase cytochrome b-556 subunit.
  
     0.618
plu0665
PseudoU_synth_2 domain-containing protein; Unnamed protein product; Highly similar to unknown protein YqcB of Escherichia coli.
  
  
 0.580
nfuA
Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
     0.505
sdhE
FAD assembly factor SdhE; An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
  
    0.477
rmf
Ribosome modulation factor (protein E); During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes); Belongs to the ribosome modulation factor family.
  
     0.474
glpG
Protein GlpG; Rhomboid-type serine protease that catalyzes intramembrane proteolysis.
  
     0.463
rdgC
Recombinaison associated protein; May be involved in recombination; Belongs to the RdgC family.
  
   
 0.431
plu0491
Unnamed protein product; Highly similar to unknown protein YjaG of Escherichia coli.
  
     0.425
plu2426
SUI1 domain-containing protein; Unnamed protein product; Highly similar to probable translation initiation factor YciH of Escherichia coli.
  
     0.417
topA
DNA topoisomerase I (omega protein) (relaxing enzyme) (untwisting enzyme) (swivelase); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then un [...]
  
     0.415
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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