STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plu0664DUF446 domain-containing protein; Unnamed protein product; Similar to unknown protein YqcC of Escherichia coli. (110 aa)    
Predicted Functional Partners:
sdhC
Succinate dehydrogenase cytochrome b-556 subunit.
  
     0.618
plu0665
PseudoU_synth_2 domain-containing protein; Unnamed protein product; Highly similar to unknown protein YqcB of Escherichia coli.
  
  
 0.508
nfuA
Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
     0.505
rmf
Ribosome modulation factor (protein E); During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes); Belongs to the ribosome modulation factor family.
  
     0.474
sdhE
FAD assembly factor SdhE; An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
  
     0.467
glpG
Protein GlpG; Rhomboid-type serine protease that catalyzes intramembrane proteolysis.
  
     0.463
plu0491
Unnamed protein product; Highly similar to unknown protein YjaG of Escherichia coli.
  
     0.425
plu2426
SUI1 domain-containing protein; Unnamed protein product; Highly similar to probable translation initiation factor YciH of Escherichia coli.
  
     0.417
topA
DNA topoisomerase I (omega protein) (relaxing enzyme) (untwisting enzyme) (swivelase); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then un [...]
  
     0.415
rnb
Exoribonuclease II (ribonuclease II) (RNase II); Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
  
     0.405
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.