| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| bvgS | metQ | plu2284 | plu0695 | Virulence sensor protein BvgS precursor. | D-methionine-binding periplasmic protein precursor MetQ; Belongs to the nlpA lipoprotein family. | 0.440 |
| gmhB1 | metI | plu0698 | plu0696 | D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase; Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position. | D-methionine transport permease protein MetI. | 0.537 |
| gmhB1 | metN | plu0698 | plu0697 | D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase; Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position. | D-methionine transport ATP-binding protein MetN; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.537 |
| gmhB1 | metQ | plu0698 | plu0695 | D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase; Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position. | D-methionine-binding periplasmic protein precursor MetQ; Belongs to the nlpA lipoprotein family. | 0.449 |
| metE | metK | plu4420 | plu3683 | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | S-adenosylmethionine synthetase (methionine adenosyltransferase) (AdoMet synthetase) (MAT); Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.976 |
| metE | metQ | plu4420 | plu0695 | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | D-methionine-binding periplasmic protein precursor MetQ; Belongs to the nlpA lipoprotein family. | 0.403 |
| metE | plu3517 | plu4420 | plu3517 | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | Unnamed protein product; Highly similar to homocysteine synthase. | 0.935 |
| metI | gmhB1 | plu0696 | plu0698 | D-methionine transport permease protein MetI. | D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase; Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position. | 0.537 |
| metI | metN | plu0696 | plu0697 | D-methionine transport permease protein MetI. | D-methionine transport ATP-binding protein MetN; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.999 |
| metI | metQ | plu0696 | plu0695 | D-methionine transport permease protein MetI. | D-methionine-binding periplasmic protein precursor MetQ; Belongs to the nlpA lipoprotein family. | 0.999 |
| metI | plu0693 | plu0696 | plu0693 | D-methionine transport permease protein MetI. | TsaA-like domain-containing protein; Unnamed protein product; Highly similar to unknown protein YaeB. | 0.466 |
| metI | rcsF | plu0696 | plu0694 | D-methionine transport permease protein MetI. | Exopolysaccharide synthesis regulatory protein RcsF; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family. | 0.453 |
| metK | metE | plu3683 | plu4420 | S-adenosylmethionine synthetase (methionine adenosyltransferase) (AdoMet synthetase) (MAT); Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.976 |
| metK | metN | plu3683 | plu0697 | S-adenosylmethionine synthetase (methionine adenosyltransferase) (AdoMet synthetase) (MAT); Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | D-methionine transport ATP-binding protein MetN; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.590 |
| metK | metQ | plu3683 | plu0695 | S-adenosylmethionine synthetase (methionine adenosyltransferase) (AdoMet synthetase) (MAT); Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | D-methionine-binding periplasmic protein precursor MetQ; Belongs to the nlpA lipoprotein family. | 0.481 |
| metN | gmhB1 | plu0697 | plu0698 | D-methionine transport ATP-binding protein MetN; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase; Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position. | 0.537 |
| metN | metI | plu0697 | plu0696 | D-methionine transport ATP-binding protein MetN; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | D-methionine transport permease protein MetI. | 0.999 |
| metN | metK | plu0697 | plu3683 | D-methionine transport ATP-binding protein MetN; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | S-adenosylmethionine synthetase (methionine adenosyltransferase) (AdoMet synthetase) (MAT); Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.590 |
| metN | metQ | plu0697 | plu0695 | D-methionine transport ATP-binding protein MetN; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | D-methionine-binding periplasmic protein precursor MetQ; Belongs to the nlpA lipoprotein family. | 0.999 |
| metN | plu0693 | plu0697 | plu0693 | D-methionine transport ATP-binding protein MetN; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | TsaA-like domain-containing protein; Unnamed protein product; Highly similar to unknown protein YaeB. | 0.492 |