Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
metID-methionine transport permease protein MetI. (217 aa)    
Predicted Functional Partners:
metQ
D-methionine-binding periplasmic protein precursor MetQ; Belongs to the nlpA lipoprotein family.
 0.999
metN
D-methionine transport ATP-binding protein MetN; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
 
 0.999
metA
Homoserine O-succinyltransferase (homoserine O-transsuccinylase) (HTS); Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.
  
    0.692
gmhB1
D-glycero-beta-D-manno-heptose-1,7-bisphosphate 7-phosphatase; Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate by removing the phosphate group at the C-7 position.
       0.545
plu0693
TsaA-like domain-containing protein; Unnamed protein product; Highly similar to unknown protein YaeB.
       0.477
metF
5,10-methylenetetrahydrofolate reductase; Truncated gene. Similar to the N-terminal region of transposase, IS630 family (ISPlu3-p); Belongs to the methylenetetrahydrofolate reductase family.
   
    0.461
rcsF
Exopolysaccharide synthesis regulatory protein RcsF; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family.
       0.455
plu1866
Bac_luciferase domain-containing protein; Unnamed protein product; Highly similar to nitrilotriacetate monooxygenase component A.
    0.422
plu0523
Unnamed protein product; Similar to cystathionine gamma-lyase.
   
    0.403
metB
Cystathionine gamma-synthase (CGS) (O-succinylhomoserine (Thiol)-lyase).
   
    0.403
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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