Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
plu0757ACP_syn_III_C domain-containing protein; Unnamed protein product; Some similarities with 3-oxoacyl-acyl carrier protein synthase III. Protein involved in antibiotics synthetis. (315 aa)    
Predicted Functional Partners:
fabD
Malonyl CoA-acyl carrier protein transacylase (MCT).
  
 
 0.963
plu0753
ACP_syn_III_C domain-containing protein; Unnamed protein product; Some similarities with 3-oxoacyl-acyl carrier protein synthase III.
 
  
 
0.944
fabB
3-oxoacyl-[acyl-carrier-protein] synthase I (beta-ketoacyl-ACP synthase I) (KAS I); 2.4; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
 
 0.939
accD
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta (ACCase beta chain); Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
  
 
 0.931
accA
acetyl-CoA carboxylase alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
  
 
 0.927
accB
Biotin carboxyl carrier protein of acetyl-CoA carboxylase (BCCP); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 
 0.924
accC
Biotin carboxylase (A subunit of acetyl-CoA carboxylase) (ACC); This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 
 0.916
plu1541
Unnamed protein product; Similar to granaticin polyketide ketoreductase and 3-ketoacyl-acyl carrier protein reductase.
  
 
 0.908
plu2075
Unnamed protein product; Similar to 3-oxoacyl-[acyl-carrier protein] reductase.
  
 
 0.908
fabG
3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 0.908
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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