STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panCPantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (284 aa)    
Predicted Functional Partners:
panD
Aspartate 1-decarboxylase precursor; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
 
 0.999
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
  
 0.999
apbA
2-dehydropantoate 2-reductase (Ketopantoate reductase); Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
    
 0.935
dfp
DNA/pantothenate metabolism flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
 
 0.930
coaA
Pantothenate kinase (pantothenic acid kinase).
     
 0.917
plu2260
Unnamed protein product; Similar to beta-alanine--pyruvate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
   
 
 0.916
mssA
Cytidylate kinase (CK) (cytidine monophosphate kinase) (CMP kinase) (MssA protein) (P25).
      0.907
plu0142
Aldedh domain-containing protein; Unnamed protein product; Similar to NADP-dependent aldehyde dehydrogenase.
     
  0.900
goaG
4-aminobutyrate aminotransferase (gamma-amino-N-butyrate transaminase) (GABA transaminase); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.900
aldB
Aldehyde dehydrogenase B (Lactaldehyde dehydrogenase); Belongs to the aldehyde dehydrogenase family.
     
  0.900
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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