node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
erpA | hscB | plu0904 | plu3280 | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | Chaperone protein hscB (HSC20); Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.624 |
erpA | iscS | plu0904 | plu3283 | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.481 |
erpA | nfuA | plu0904 | plu0198 | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.617 |
erpA | nifU | plu0904 | plu3282 | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | NifU protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.610 |
erpA | plu2262 | plu0904 | plu2262 | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | Unnamed protein product; Some similarities with molybdopterin oxidoreductase and dimethylsulfoxide reductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.492 |
erpA | plu2604 | plu0904 | plu2604 | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | Glutaredoxin; Unnamed protein product; Highly similar to probable glutaredoxin-like protein YdhD of Escherichia coli; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.560 |
erpA | plu3556 | plu0904 | plu3556 | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | tRNA-modifying protein YgfZ; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. | 0.522 |
erpA | plu4673 | plu0904 | plu4673 | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | NifU_N domain-containing protein; Unnamed protein product; Some similarities with nitrogen fixation proteins. | 0.599 |
erpA | sufB | plu0904 | plu2621 | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | SufB protein. | 0.487 |
erpA | sufD | plu0904 | plu2619 | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | SufD protein. | 0.559 |
hscB | erpA | plu3280 | plu0904 | Chaperone protein hscB (HSC20); Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | 0.624 |
hscB | iscS | plu3280 | plu3283 | Chaperone protein hscB (HSC20); Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.896 |
hscB | nfuA | plu3280 | plu0198 | Chaperone protein hscB (HSC20); Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.802 |
hscB | nifU | plu3280 | plu3282 | Chaperone protein hscB (HSC20); Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | NifU protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.986 |
hscB | plu2262 | plu3280 | plu2262 | Chaperone protein hscB (HSC20); Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | Unnamed protein product; Some similarities with molybdopterin oxidoreductase and dimethylsulfoxide reductase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.421 |
hscB | plu4673 | plu3280 | plu4673 | Chaperone protein hscB (HSC20); Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | NifU_N domain-containing protein; Unnamed protein product; Some similarities with nitrogen fixation proteins. | 0.927 |
iscS | erpA | plu3283 | plu0904 | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. | 0.481 |
iscS | hscB | plu3283 | plu3280 | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | Chaperone protein hscB (HSC20); Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.896 |
iscS | nfuA | plu3283 | plu0198 | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | Fe/S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.846 |
iscS | nifU | plu3283 | plu3282 | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | NifU protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.994 |