Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hpaARegulator of the 4HPA-hydroxylase operon. (296 aa)    
Predicted Functional Partners:
hpcB
3,4-dihydroxyphenylacetate 2,3-dioxygenase.
 
  
 0.955
hpcD
5-carboxymethyl-2-hydroxy-muconic acid isomerase.
 
  
 0.930
hpaX
4-hydroxyphenylacetate permease.
 
  
 0.912
hpaI
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Belongs to the HpcH/HpaI aldolase family.
 
    0.842
hpcG
2-oxo-hepta-3-ene-1,7-dioic acid hydratase.
 
    0.817
hpcR
Homoprotocatechuate degradation operon regulator.
 
  
 0.772
plu2321
Unnamed protein product; Similar to protein HMWP1 of Yersinia enterocolitica.
 
   
 0.758
hpaG2
HpaG2 protein; Similar to C-terminal region of 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase HpaG [Includes: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase); 5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase (OPET decarboxylase)].
 
  
 0.743
hpaG1
HpaG1 protein; Similar to N-terminal region of 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase HpaG [Includes: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase); 5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase (OPET decarboxylase)].
 
  
 0.717
plu1880
Unnamed protein product; Similar to proteins involved in antibiotic biosynthesis. Putative transmembrane protein.
  
  
 0.662
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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