Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hpaX4-hydroxyphenylacetate permease. (458 aa)    
Predicted Functional Partners:
hpaA
Regulator of the 4HPA-hydroxylase operon.
 
  
 0.912
hpcB
3,4-dihydroxyphenylacetate 2,3-dioxygenase.
 
    0.802
hpaI
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Belongs to the HpcH/HpaI aldolase family.
  
  
 0.770
hpcD
5-carboxymethyl-2-hydroxy-muconic acid isomerase.
 
    0.758
hpcG
2-oxo-hepta-3-ene-1,7-dioic acid hydratase.
 
    0.735
hpaG1
HpaG1 protein; Similar to N-terminal region of 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase HpaG [Includes: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase); 5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase (OPET decarboxylase)].
 
    0.592
hpaG2
HpaG2 protein; Similar to C-terminal region of 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase HpaG [Includes: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase); 5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase (OPET decarboxylase)].
  
    0.571
gabD
Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
       0.555
plu0985
Bcr/CflA family efflux transporter; Unnamed protein product; Some similarities with probable MFS transporter.
  
    0.555
plu1880
Unnamed protein product; Similar to proteins involved in antibiotic biosynthesis. Putative transmembrane protein.
     
 0.523
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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