STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hpcG2-oxo-hepta-3-ene-1,7-dioic acid hydratase. (267 aa)    
Predicted Functional Partners:
hpaI
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Belongs to the HpcH/HpaI aldolase family.
 
 0.999
hpcD
5-carboxymethyl-2-hydroxy-muconic acid isomerase.
 
  
 0.978
hpcB
3,4-dihydroxyphenylacetate 2,3-dioxygenase.
 
  
 0.978
hpaG2
HpaG2 protein; Similar to C-terminal region of 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase HpaG [Includes: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase); 5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase (OPET decarboxylase)].
 
 
 0.977
hpaG1
HpaG1 protein; Similar to N-terminal region of 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase HpaG [Includes: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase); 5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase (OPET decarboxylase)].
 
 
 0.976
hpaA
Regulator of the 4HPA-hydroxylase operon.
 
    0.792
hpcR
Homoprotocatechuate degradation operon regulator.
 
     0.791
gabD
Succinate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
  
 0.787
plu0985
Bcr/CflA family efflux transporter; Unnamed protein product; Some similarities with probable MFS transporter.
  
    0.774
hpcC
5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
  
 0.729
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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