Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
plu1195YkuD domain-containing protein; Unnamed protein product; Similar to putative exported protein YafK of Escherichia coli. (247 aa)    
Predicted Functional Partners:
plu2582
Unnamed protein product; Highly similar to unknown protein YcjX of Escherichia coli (putative EC 2.1 enzyme).
  
     0.504
lapB
Lipopolysaccharide assembly protein B; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.
      
 0.496
plu3845
Unnamed protein product; Similar to 2Fe-2S ferredoxin, iron-sulfur binding protein.
  
     0.475
topA
DNA topoisomerase I (omega protein) (relaxing enzyme) (untwisting enzyme) (swivelase); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then un [...]
       0.439
plu2616
LysM domain-containing protein; Unnamed protein product; Highly similar to unknown protein YnhG precursor and YcfS precursor of Escherichia coli.
 
  
 0.432
plu1748
Uncharacterized protein; Truncated gene. Similar to C-terminal part of putative amidase YcbB precursor of Escherichia coli.
  
    0.418
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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