STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gshAGlutamate--cysteine ligase (Gamma-glutamylcysteine synthetase) (Gamma-ECS) (GCS); Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. (519 aa)    
Predicted Functional Partners:
pepN
Aminopeptidase N.
     
 0.952
gshB
Glutathione synthase (glutathione synthase) (GSH synthetase) (GSH-S).
 
 
 0.942
pepD
Aminoacyl-histidine dipeptidase (XAA-His dipeptidase) (beta-alanyl-histidine dipeptidase) (carnosinase) (peptidase D).
   
 
 0.911
ggt
Gamma-glutamyltranspeptidase.
    
  0.908
pepA
Cytosol aminopeptidase (leucine aminopeptidase) (LAP) (leucyl aminopeptidase) (aminopeptidase A/I); Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
     
 0.906
pepB
Peptidase B (Aminopeptidase B); Probably plays an important role in intracellular peptide degradation.
     
 0.904
plu1438
Unnamed protein product; Similar to branched-chain amino acid aminotransferases.
     
  0.900
aspC
Aspartate aminotransferase (transaminase A).
     
 0.900
ilvE-2
Branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
     
  0.900
pxpA
5-oxoprolinase subunit A; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
     
  0.900
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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