Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
emrAMultidrug resistant protein A. (394 aa)    
Predicted Functional Partners:
emrB
Multidrug resistance protein B; Belongs to the major facilitator superfamily.
 
 
 0.981
plu4680
MFS domain-containing protein; Unnamed protein product; Highly similar to multidrug resistance protein B; Belongs to the major facilitator superfamily.
 
 
 0.909
plu2199
MFS domain-containing protein; Unnamed protein product; Similar to transporter.
 
 
 0.715
plu0061
MFS domain-containing protein; Unnamed protein product; Highly similar to hypothetical transport protein YieO of Escherichia coli; Belongs to the major facilitator superfamily.
  
     0.673
mprA
Transcriptional repressor mprA (EmrR protein).
 
  
 0.654
plu3924
Unnamed protein product; Similar to probable MFS transporter.
 
 
 0.616
prtD
Outer membrane protein PrtD.
  
 
 0.584
tolC
Outer membrane protein precursor TolC.
  
 
 0.584
macB
Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
  
 0.580
plu3561
MFS domain-containing protein; Unnamed protein product; Similar to proton antiporter efflux pump. Putative transmembrane protein.
 
 
 0.527
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.