| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cobB | nadD | plu2811 | plu1300 | CobB protein; Belongs to the sirtuin family. Class III subfamily. | Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.927 |
| cobB | nadE | plu2811 | plu3310 | CobB protein; Belongs to the sirtuin family. Class III subfamily. | NH(3)-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.936 |
| cobB | nadR | plu2811 | plu0553 | CobB protein; Belongs to the sirtuin family. Class III subfamily. | Transcriptional regulator NadR. | 0.987 |
| cobB | pntA | plu2811 | plu2167 | CobB protein; Belongs to the sirtuin family. Class III subfamily. | NAD(P) transhydrogenase subunit alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | 0.903 |
| cobB | ppnK | plu2811 | plu3373 | CobB protein; Belongs to the sirtuin family. Class III subfamily. | Probable inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NAD kinase); Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.914 |
| nadC | nadD | plu3637 | plu1300 | Nicotinate-nucleotide pyrophosphorylase [carboxylating] (quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase); Belongs to the NadC/ModD family. | Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.952 |
| nadC | nadE | plu3637 | plu3310 | Nicotinate-nucleotide pyrophosphorylase [carboxylating] (quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase); Belongs to the NadC/ModD family. | NH(3)-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.683 |
| nadC | nadR | plu3637 | plu0553 | Nicotinate-nucleotide pyrophosphorylase [carboxylating] (quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase); Belongs to the NadC/ModD family. | Transcriptional regulator NadR. | 0.950 |
| nadC | pcnB-2 | plu3637 | plu1754 | Nicotinate-nucleotide pyrophosphorylase [carboxylating] (quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase); Belongs to the NadC/ModD family. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.970 |
| nadC | plu1248 | plu3637 | plu1248 | Nicotinate-nucleotide pyrophosphorylase [carboxylating] (quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase); Belongs to the NadC/ModD family. | CinA domain-containing protein; Unnamed protein product; Similar to unknown protein YgaD of Escherichia coli; Belongs to the CinA family. | 0.924 |
| nadC | ushA | plu3637 | plu3828 | Nicotinate-nucleotide pyrophosphorylase [carboxylating] (quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase); Belongs to the NadC/ModD family. | Protein UshA precursor [Includes: UDP-sugar hydrolase (UDP-sugar diphosphatase) (UDP-sugar pyrophosphatase); 5'-nucleotidase (5'-NT)]; Belongs to the 5'-nucleotidase family. | 0.900 |
| nadD | cobB | plu1300 | plu2811 | Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | CobB protein; Belongs to the sirtuin family. Class III subfamily. | 0.927 |
| nadD | nadC | plu1300 | plu3637 | Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Nicotinate-nucleotide pyrophosphorylase [carboxylating] (quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase); Belongs to the NadC/ModD family. | 0.952 |
| nadD | nadE | plu1300 | plu3310 | Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NH(3)-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.968 |
| nadD | nadR | plu1300 | plu0553 | Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Transcriptional regulator NadR. | 0.950 |
| nadD | pcnB-2 | plu1300 | plu1754 | Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.954 |
| nadD | plu1248 | plu1300 | plu1248 | Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | CinA domain-containing protein; Unnamed protein product; Similar to unknown protein YgaD of Escherichia coli; Belongs to the CinA family. | 0.962 |
| nadD | pntA | plu1300 | plu2167 | Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NAD(P) transhydrogenase subunit alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | 0.903 |
| nadD | ppnK | plu1300 | plu3373 | Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Probable inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NAD kinase); Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.947 |
| nadD | rsfS | plu1300 | plu1299 | Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Ribosomal silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.910 |