Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
rtxBRTX toxin ABC transporter (IM-ABC) protein RtxB. (701 aa)    
Predicted Functional Partners:
rtxD
RTX toxin ABC transporter protein (MFP) RtxD.
 
 
 0.985
plu0635
Unnamed protein product; Similar to hemolysin export system membrane fusion protein HlyD of Escherichia coli (hemolysin secretion protein D).
 
 
 0.929
plu3125
Unnamed protein product; Similar to toxin secretion transporter.
  
  
 
0.903
plu1331
Unnamed protein product; Similar to unknown protein VC1446 of Vibrio cholerae, probable RTX toxin ABC transporter (IM-ABC) protein.
 
  
 
0.868
plu3126
Unnamed protein product; Similar to toxin secretion transporter (Membrane Fusion Protein (MFP)).
 
 
 0.856
plu3668
Unnamed protein product; Similar to unknown protein of Photorhabdus and some similarities with Fe-regulated RTX cytotoxin.
 
  
 0.812
plu4117
Unnamed protein product; Similar to unknown protein of Photorhabdus and some similarities with Fe-regulated RTX cytotoxin and hemolysin-type calcium binding protein.
 
  
 0.807
prtC
Membrane Fusion Protein PrtC.
 
 
 0.774
rtxC
Cytolysin-activating lysine-acyltransferase RtxC.
 
   
 0.763
afuC
ABC transporter ATP-binding protein AfuC; Part of the ABC transporter complex FbpABC involved in Fe(3+) ions import. Responsible for energy coupling to the transport system.
     
0.742
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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