Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
crrPTS system, glucose-specific IIA component (EIIA-GLC) (Glucose-permease IIA component) (Phosphotransferase enzyme II, A component) (EIII-GLC). (169 aa)    
Predicted Functional Partners:
nagE
PTS system, N-acetylglucosamine-specific IIABC component (EIIABC-NAG) (N-acetylglucosamine-permease IIABC component) (Phosphotransferase enzyme II, ABC component) (EII-NAG).
 0.999
ptsI
Phosphoenolpyruvate-protein phosphotransferase (Phosphotransferase system, enzyme I); General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.999
ptsH
Phosphocarrier protein HPr (Histidine-containing protein).
 
 0.999
plu1989
Unnamed protein product; Highly similar to phosphotransferase system enzyme II.
 0.999
murP
N-acetylmuramic acid-specific phosphotransferase enzyme IIB component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in N-acetylmuramic acid (MurNAc) transport, yielding cytoplasmic MurNAc-6-P. Is also able to take up anhydro-N-acetylmuramic acid (anhMurNAc), but cannot phosphorylate the carbon 6, probably because of the 1,6-anhydro ring.
 0.998
treB
PTS system, trehalose-specific IIBC component (EIIBC-TRE) (trehalose-permease IIBC component) (phosphotransferase enzyme II, BC component) (EII-TRE).
 0.998
bglF
Beta-glucoside-specific phosphotransferase system-dependent permease.
 
 0.987
nagA
N-acetylglucosamine-6-phosphate deacetylase (GLCNAC 6-P deacetylase).
 
  
 0.935
bglB
6-phospho-beta-glucosidase B; Belongs to the glycosyl hydrolase 1 family.
 
 
 0.923
bglA
6-phospho-beta-glucosidase A; Belongs to the glycosyl hydrolase 1 family.
 
 
 0.923
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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