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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptsIPhosphoenolpyruvate-protein phosphotransferase (Phosphotransferase system, enzyme I); General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (575 aa)    
Predicted Functional Partners:
ptsH
Phosphocarrier protein HPr (Histidine-containing protein).
 
 0.999
fruB
PTS system, fructose-specific IIA/FPr component.
 0.999
crr
PTS system, glucose-specific IIA component (EIIA-GLC) (Glucose-permease IIA component) (Phosphotransferase enzyme II, A component) (EIII-GLC).
 
 0.998
fruA
PTS system, fructose-specific IIBC component.
 
  
 0.969
ptsO
Phosphocarrier protein NPr (nitrogen related HPr).
 
 
 0.953
plu0585
Unnamed protein product; Similar to beta-glucoside permease IIABC component (phosphotransferase enzyme II, ABC component). Putative transmembrane protein.
 
 0.947
fruK
1-phosphofructokinase (fructose 1-phosphate kinase); Belongs to the carbohydrate kinase PfkB family.
 
  
 0.855
nagE
PTS system, N-acetylglucosamine-specific IIABC component (EIIABC-NAG) (N-acetylglucosamine-permease IIABC component) (Phosphotransferase enzyme II, ABC component) (EII-NAG).
  
 0.824
ptsN
Nitrogen regulatory IIA protein (enzyme IIA-NTR) (phosphotransferase enzyme II, A component).
 
  
 0.792
plu1989
Unnamed protein product; Highly similar to phosphotransferase system enzyme II.
  
 0.785
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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