Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ptsHPhosphocarrier protein HPr (Histidine-containing protein). (85 aa)    
Predicted Functional Partners:
crr
PTS system, glucose-specific IIA component (EIIA-GLC) (Glucose-permease IIA component) (Phosphotransferase enzyme II, A component) (EIII-GLC).
 
 0.999
ptsI
Phosphoenolpyruvate-protein phosphotransferase (Phosphotransferase system, enzyme I); General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.999
fruA
PTS system, fructose-specific IIBC component.
 
 
 0.990
manX
PTS system, mannose-specific IIAB component (EIIAB-MAN) (Mannose-permease IIAB component) (Phosphotransferase enzyme II, AB component) (EIII-MAN).
  
 0.981
plu0585
Unnamed protein product; Similar to beta-glucoside permease IIABC component (phosphotransferase enzyme II, ABC component). Putative transmembrane protein.
  
 0.967
celC
PTS system, cellobiose-specific IIA component (EIIA-CEL) (Cellobiose-permease IIA component) (Phosphotransferase enzyme II, A component) (EIII-CEL).
   
 0.962
nagE
PTS system, N-acetylglucosamine-specific IIABC component (EIIABC-NAG) (N-acetylglucosamine-permease IIABC component) (Phosphotransferase enzyme II, ABC component) (EII-NAG).
 
 
 0.955
plu1989
Unnamed protein product; Highly similar to phosphotransferase system enzyme II.
 
 
 0.938
fruB
PTS system, fructose-specific IIA/FPr component.
 
 
0.934
treB
PTS system, trehalose-specific IIBC component (EIIBC-TRE) (trehalose-permease IIBC component) (phosphotransferase enzyme II, BC component) (EII-TRE).
  
 
 0.934
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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