Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cysKCysteine synthase A (O-acetylserine sulfhydrolase A); Belongs to the cysteine synthase/cystathionine beta- synthase family. (317 aa)    
Predicted Functional Partners:
cysE
Serine acetyltransferase (SAT).
 
 0.987
metC
Cystathionine beta-lyase (CHL) (beta-cystathionase) (cysteine lyase).
 
 0.950
cysJ
Sulfite reductase [NADPH] flavoprotein alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
  
 
 0.949
cysI
Sulfite reductase [NADPH] hemoprotein beta-component (SIR-HP); Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
 
 0.942
plu0523
Unnamed protein product; Similar to cystathionine gamma-lyase.
  
 0.941
metB
Cystathionine gamma-synthase (CGS) (O-succinylhomoserine (Thiol)-lyase).
  
 0.941
plu2021
Serine acetyltransferase; Unnamed protein product; Some similarities with serine O-acetyltransferase.
 
 0.909
plu3861
PALP domain-containing protein; Unnamed protein product; Similar to cysteine synthase.
  
  
 
0.909
plu3731
Aminotran_1_2 domain-containing protein; Unnamed protein product; Similar to aminotransferases.
    
 0.907
serC
3-phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
    
 0.905
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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