| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aceF | lpdA | plu3622 | plu3621 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (E2); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoamide dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (glycine cleavage system L protein). | 0.997 |
| aceF | nuoC | plu3622 | plu3087 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (E2); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | NADH dehydrogenase I chain C/D (NADH-ubiquinone oxidoreductase chain 3/4) (NUO3/NUO4); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.693 |
| aceF | sucA | plu3622 | plu1430 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (E2); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 2-oxoglutarate dehydrogenase E1 component (Alpha-ketoglutarate dehydrogenase). | 0.958 |
| aceF | sucC | plu3622 | plu1432 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (E2); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.939 |
| aceF | sucD | plu3622 | plu1433 | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (E2); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.926 |
| icd | nuoC | plu2801 | plu3087 | Isocitrate dehydrogenase [NADP]. | NADH dehydrogenase I chain C/D (NADH-ubiquinone oxidoreductase chain 3/4) (NUO3/NUO4); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.783 |
| icd | plu2796 | plu2801 | plu2796 | Isocitrate dehydrogenase [NADP]. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Unnamed protein product; C terminal part similar to peptide synthetase. Putative transmembrane protein. | 0.413 |
| icd | sdhC | plu2801 | plu1426 | Isocitrate dehydrogenase [NADP]. | Succinate dehydrogenase cytochrome b-556 subunit. | 0.460 |
| icd | sucA | plu2801 | plu1430 | Isocitrate dehydrogenase [NADP]. | 2-oxoglutarate dehydrogenase E1 component (Alpha-ketoglutarate dehydrogenase). | 0.973 |
| icd | sucC | plu2801 | plu1432 | Isocitrate dehydrogenase [NADP]. | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.889 |
| icd | sucD | plu2801 | plu1433 | Isocitrate dehydrogenase [NADP]. | succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.774 |
| lpdA | aceF | plu3621 | plu3622 | Dihydrolipoamide dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (glycine cleavage system L protein). | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (E2); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.997 |
| lpdA | nuoC | plu3621 | plu3087 | Dihydrolipoamide dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (glycine cleavage system L protein). | NADH dehydrogenase I chain C/D (NADH-ubiquinone oxidoreductase chain 3/4) (NUO3/NUO4); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.604 |
| lpdA | plu1884 | plu3621 | plu1884 | Dihydrolipoamide dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (glycine cleavage system L protein). | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Unnamed protein product; Some similarities with dihydrolipoamide acyltransferase and succinyltransferase. | 0.990 |
| lpdA | plu2796 | plu3621 | plu2796 | Dihydrolipoamide dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (glycine cleavage system L protein). | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Unnamed protein product; C terminal part similar to peptide synthetase. Putative transmembrane protein. | 0.902 |
| lpdA | sucA | plu3621 | plu1430 | Dihydrolipoamide dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (glycine cleavage system L protein). | 2-oxoglutarate dehydrogenase E1 component (Alpha-ketoglutarate dehydrogenase). | 0.983 |
| lpdA | sucB | plu3621 | plu1431 | Dihydrolipoamide dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (glycine cleavage system L protein). | Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex (E2); E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.994 |
| lpdA | sucC | plu3621 | plu1432 | Dihydrolipoamide dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (glycine cleavage system L protein). | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.464 |
| nuoC | aceF | plu3087 | plu3622 | NADH dehydrogenase I chain C/D (NADH-ubiquinone oxidoreductase chain 3/4) (NUO3/NUO4); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (E2); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.693 |
| nuoC | icd | plu3087 | plu2801 | NADH dehydrogenase I chain C/D (NADH-ubiquinone oxidoreductase chain 3/4) (NUO3/NUO4); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | Isocitrate dehydrogenase [NADP]. | 0.783 |
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