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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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filled nodes:
a 3D structure is known or predicted
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sucA2-oxoglutarate dehydrogenase E1 component (Alpha-ketoglutarate dehydrogenase). (935 aa)    
Predicted Functional Partners:
sucB
Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex (E2); E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.999
sucC
succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 0.995
sucD
succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.988
lpdA
Dihydrolipoamide dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (glycine cleavage system L protein).
 
 0.982
icd
Isocitrate dehydrogenase [NADP].
   
 0.981
aceF
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (E2); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.974
sdhB
Succinate dehydrogenase iron sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 
 0.950
plu1884
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Unnamed protein product; Some similarities with dihydrolipoamide acyltransferase and succinyltransferase.
 
 0.950
nuoC
NADH dehydrogenase I chain C/D (NADH-ubiquinone oxidoreductase chain 3/4) (NUO3/NUO4); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
   
 0.938
sdhC
Succinate dehydrogenase cytochrome b-556 subunit.
  
  
 0.936
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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