Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
plu1437FAD_binding_3 domain-containing protein; Unnamed protein product; Similar to 3-(3-hydroxy-phenyl) propionate hydroxylase MphA protein of Escherichia coli. (540 aa)    
Predicted Functional Partners:
mhpB
2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase; Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6- ketononatrienedioate, respectively; Belongs to the LigB/MhpB extradiol dioxygenase family.
 
  
 0.928
hcaB
2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase; Converts 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol) into 3-(2,3- dihydroxylphenyl)propanoic acid (DHPP) and 2,3-dihydroxicinnamic acid (DHCI), respectively; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
  0.900
plu1436
Unnamed protein product; Hypothetical protein.
     
 0.765
plu1434
Unnamed protein product; Some similarities with putative oxidoreductase.
 
   
 0.701
plu1435
Aminotran_5 domain-containing protein; Unnamed protein product; Some similarities with aminotransferase. Putative transmembrane protein.
       0.649
plu1743
FAD_binding_3 domain-containing protein; Unnamed protein product; Similar to putative monooxygenase.
  
   
 0.568
plu2236
FAD_binding_3 domain-containing protein; Unnamed protein product; Some similarities with probable monooxygenase.
  
   
 0.553
plu1439
Unnamed protein product; Similar to unknown protein.
 
     0.524
plu1219
Unnamed protein product; Similar to Sim-nI, NovI and KikQ (cytochromes P-450), proteins involved in antibiotic biosynthesis.
  
 
 0.503
plu1438
Unnamed protein product; Similar to branched-chain amino acid aminotransferases.
       0.461
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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