Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
plu1515ThiF domain-containing protein; Unnamed protein product; Similar to MccB protein of Escherichia coli, involved in the production of microcin C7. (352 aa)    
Predicted Functional Partners:
moaD
Sulfur-carrier protein; Molybdopterin [mpt] converting factor, subunit 1 (molybdenum cofactor biosynthesis protein D) (molybdopterin converting factor small subunit).
  
 0.959
moeB
Molybdopterin biosynthesis protein.
  
  
 
0.927
plu0915
Cysteine desulfurase; Unnamed protein product; Similar to cysteine desulfurase (NifS protein homolog).
   
 0.926
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
   
 0.926
plu4674
Aminotran_5 domain-containing protein; Unnamed protein product; Some similarities with NifS protein, a cysteine desulfurase.
   
 0.926
plu3103
Aminotran_5 domain-containing protein; Unnamed protein product; Similar to cysteine desulfurase (NifS protein homolog).
   
 0.924
thiG
Thiamin biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.853
thiS
ThiS protein.
  
 
 0.852
thiH
Thiamin biosynthesis, thiazole moiety.
 
  
 0.823
moaE
Molybdopterin [MPT] converting factor, subunit 2 (molybdenum cofactor biosynthesis protein E) (molybdopterin converting factor large subunit).
 
 0.802
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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