STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folEGTP cyclohydrolase I (GTP-CH-I). (219 aa)    
Predicted Functional Partners:
folK
7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.
  
 0.992
ribA
GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
 
 
 
 0.963
folP
Dihydropteroate synthase (DHPS) (Dihydropteroate pyrophosphorylase); Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
  
 0.951
plu0702
6-carboxy-5,6,7,8-tetrahydropterin synthase; Unnamed protein product; Highly similar to putative 6-pyruvoyl tetrahydrobiopterin synthase (PTPS).
  
 
 0.941
plu2794
Unnamed protein product; Some similarities with 6-pyruvoyl tetrahydrobiopterin synthase.
  
 
 0.938
plu2793
GTP_cyclohydroI domain-containing protein; Unnamed protein product; Some similarities with GTP cyclohydrolase I precursor.
  
  
 
0.921
plu2474
GTP_cyclohydro2 domain-containing protein; Unnamed protein product; Similar to GTP cyclohydrolase II, encoded by the toxB gene of Burkholderia glumae, involved in toxoflavin biosynthesis.
 
 
 
 0.919
folB
Dihydroneopterin aldolase (DHNA); Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
  
 0.919
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
    
  0.905
nudB
dATP pyrophosphohydrolase.
    
  0.905
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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