node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
folB | folE | plu3974 | plu1543 | Dihydroneopterin aldolase (DHNA); Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase I (GTP-CH-I). | 0.919 |
folB | folK | plu3974 | plu0873 | Dihydroneopterin aldolase (DHNA); Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | 0.993 |
folB | folP | plu3974 | plu4534 | Dihydroneopterin aldolase (DHNA); Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Dihydropteroate synthase (DHPS) (Dihydropteroate pyrophosphorylase); Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.997 |
folB | plu2793 | plu3974 | plu2793 | Dihydroneopterin aldolase (DHNA); Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP_cyclohydroI domain-containing protein; Unnamed protein product; Some similarities with GTP cyclohydrolase I precursor. | 0.837 |
folB | ribA | plu3974 | plu2431 | Dihydroneopterin aldolase (DHNA); Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. | 0.584 |
folE | folB | plu1543 | plu3974 | GTP cyclohydrolase I (GTP-CH-I). | Dihydroneopterin aldolase (DHNA); Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.919 |
folE | folK | plu1543 | plu0873 | GTP cyclohydrolase I (GTP-CH-I). | 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | 0.992 |
folE | folP | plu1543 | plu4534 | GTP cyclohydrolase I (GTP-CH-I). | Dihydropteroate synthase (DHPS) (Dihydropteroate pyrophosphorylase); Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.951 |
folE | moaA | plu1543 | plu1499 | GTP cyclohydrolase I (GTP-CH-I). | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.905 |
folE | nudB | plu1543 | plu2108 | GTP cyclohydrolase I (GTP-CH-I). | dATP pyrophosphohydrolase. | 0.905 |
folE | plu0702 | plu1543 | plu0702 | GTP cyclohydrolase I (GTP-CH-I). | 6-carboxy-5,6,7,8-tetrahydropterin synthase; Unnamed protein product; Highly similar to putative 6-pyruvoyl tetrahydrobiopterin synthase (PTPS). | 0.941 |
folE | plu2474 | plu1543 | plu2474 | GTP cyclohydrolase I (GTP-CH-I). | GTP_cyclohydro2 domain-containing protein; Unnamed protein product; Similar to GTP cyclohydrolase II, encoded by the toxB gene of Burkholderia glumae, involved in toxoflavin biosynthesis. | 0.919 |
folE | plu2793 | plu1543 | plu2793 | GTP cyclohydrolase I (GTP-CH-I). | GTP_cyclohydroI domain-containing protein; Unnamed protein product; Some similarities with GTP cyclohydrolase I precursor. | 0.921 |
folE | plu2794 | plu1543 | plu2794 | GTP cyclohydrolase I (GTP-CH-I). | Unnamed protein product; Some similarities with 6-pyruvoyl tetrahydrobiopterin synthase. | 0.938 |
folE | ribA | plu1543 | plu2431 | GTP cyclohydrolase I (GTP-CH-I). | GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. | 0.963 |
folK | folB | plu0873 | plu3974 | 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | Dihydroneopterin aldolase (DHNA); Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.993 |
folK | folE | plu0873 | plu1543 | 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | GTP cyclohydrolase I (GTP-CH-I). | 0.992 |
folK | folP | plu0873 | plu4534 | 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | Dihydropteroate synthase (DHPS) (Dihydropteroate pyrophosphorylase); Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
folK | plu2793 | plu0873 | plu2793 | 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | GTP_cyclohydroI domain-containing protein; Unnamed protein product; Some similarities with GTP cyclohydrolase I precursor. | 0.880 |
folK | ribA | plu0873 | plu2431 | 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. | 0.572 |