STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dacCSerine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6); Penicillin-binding protein 6 precursor (D-alanyl-D-alanine carboxypeptidase fraction C) (DD-pept (DD-carboxypeptidase) (PBP-6)idase); Belongs to the peptidase S11 family. (400 aa)    
Predicted Functional Partners:
mrcA
Penicillin-binding protein 1A (PBP-1a) (PBP1a) (penicillin-binding protein A) [Includes: Penicillin-insensitive transglycosylase (Peptidoglycan TGase); Penicillin-sensitive transpeptidase (DD-transpeptidase)].
     
 0.915
dacB
Penicillin-binding protein 4 precursor (PBP-4) [Includes: D-alanyl-D-alanine carboxypeptidase (DD-peptidase) (DD-carboxypeptidase); D-alanyl-D-alanine-endopeptidase (DD-endopeptidase)].
     
 0.915
dacA
Serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6); Penicillin-binding protein 5 precursor (D-alanyl-D-alanine carboxypeptidase fraction A) (DD-peptidase) (DD-caroboxypeptidase) (PBP-5); Belongs to the peptidase S11 family.
  
  
 
0.902
ftsI
Peptidoglycan synthetase ftsI precursor (penicillin-binding protein 3) (PBP-3); Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
  
 
 0.634
mtgA
Monofunctional biosynthetic peptidoglycan transglycosylase (monofunctional TGase); Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.
  
 
 0.561
secB
Protein-export protein SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.
  
     0.423
mreC
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
 
  
 0.401
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.