| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| acrA | macB | plu3851 | plu1591 | Acriflavin resistance protein A precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.915 |
| acrA | plu0759 | plu3851 | plu0759 | Acriflavin resistance protein A precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | HlyD_D23 domain-containing protein; Unnamed protein product; Some similarities with multidrug efflux membrane fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.935 |
| acrA | plu2646 | plu3851 | plu2646 | Acriflavin resistance protein A precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Unnamed protein product; Similar to Outer Membrane Factor (OMF) of ABC transport system. | 0.416 |
| acrA | plu2734 | plu3851 | plu2734 | Acriflavin resistance protein A precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | HlyD_D23 domain-containing protein; Unnamed protein product; Membrane fusion protein (MPF) component of efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.570 |
| acrA | prtD | plu3851 | plu0659 | Acriflavin resistance protein A precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Outer membrane protein PrtD. | 0.501 |
| acrA | tolC | plu3851 | plu3954 | Acriflavin resistance protein A precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Outer membrane protein precursor TolC. | 0.974 |
| lolC | lolE | plu2814 | plu2812 | Lipoprotein releasing system transmembrane protein lolC. | Lipoprotein releasing system transmembrane protein lolE. | 0.983 |
| lolC | macB | plu2814 | plu1591 | Lipoprotein releasing system transmembrane protein lolC. | Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.849 |
| lolE | lolC | plu2812 | plu2814 | Lipoprotein releasing system transmembrane protein lolE. | Lipoprotein releasing system transmembrane protein lolC. | 0.983 |
| lolE | macB | plu2812 | plu1591 | Lipoprotein releasing system transmembrane protein lolE. | Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.849 |
| macA | macB | plu1590 | plu1591 | Macrolide-specific efflux protein MacA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.975 |
| macA | plu2646 | plu1590 | plu2646 | Macrolide-specific efflux protein MacA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Unnamed protein product; Similar to Outer Membrane Factor (OMF) of ABC transport system. | 0.491 |
| macA | prtD | plu1590 | plu0659 | Macrolide-specific efflux protein MacA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Outer membrane protein PrtD. | 0.425 |
| macA | tolC | plu1590 | plu3954 | Macrolide-specific efflux protein MacA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | Outer membrane protein precursor TolC. | 0.425 |
| macB | acrA | plu1591 | plu3851 | Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Acriflavin resistance protein A precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.915 |
| macB | lolC | plu1591 | plu2814 | Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Lipoprotein releasing system transmembrane protein lolC. | 0.849 |
| macB | lolE | plu1591 | plu2812 | Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Lipoprotein releasing system transmembrane protein lolE. | 0.849 |
| macB | macA | plu1591 | plu1590 | Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Macrolide-specific efflux protein MacA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.975 |
| macB | mdtA | plu1591 | plu2774 | Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | Multidrug resistance protein MdtA; Unnamed protein product; Similar to putative membrane protein YegM of Escherichia coli; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.897 |
| macB | plu0759 | plu1591 | plu0759 | Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | HlyD_D23 domain-containing protein; Unnamed protein product; Some similarities with multidrug efflux membrane fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. | 0.897 |