macB protein (Photorhabdus laumondii) - STRING interaction network

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macB

Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (647 aa)

Predicted Functional Partners:

macA

0.959

plu2734

0.957

plu2736

0.952

plu2735

0.941

acrA

0.839

plu0759

0.806

mdtA

0.806

plu2321

0.770

bvgS

0.710

hslJ

0.691

Your Current Organism:

Photorhabdus laumondii

NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
acrA	macB	plu3851	plu1591	Acriflavin resistance protein A precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	0.839
acrA	mdtA	plu3851	plu2774	Acriflavin resistance protein A precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Multidrug resistance protein MdtA; Unnamed protein product; Similar to putative membrane protein YegM of Escherichia coli; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.414
acrA	plu0759	plu3851	plu0759	Acriflavin resistance protein A precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	HlyD_D23 domain-containing protein; Unnamed protein product; Some similarities with multidrug efflux membrane fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.937
acrA	plu2734	plu3851	plu2734	Acriflavin resistance protein A precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	HlyD_D23 domain-containing protein; Unnamed protein product; Membrane fusion protein (MPF) component of efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.570
acrA	plu2736	plu3851	plu2736	Acriflavin resistance protein A precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Unnamed protein product; Similar to ABC transporter (permease subunit).	0.429
bvgS	macB	plu2284	plu1591	Virulence sensor protein BvgS precursor.	Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	0.710
bvgS	plu2321	plu2284	plu2321	Virulence sensor protein BvgS precursor.	Unnamed protein product; Similar to protein HMWP1 of Yersinia enterocolitica.	0.879
hslJ	macB	plu2144	plu1591	Heat shock protein HslJ.	Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	0.691
macA	macB	plu1590	plu1591	Macrolide-specific efflux protein MacA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	0.959
macA	mdtA	plu1590	plu2774	Macrolide-specific efflux protein MacA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Multidrug resistance protein MdtA; Unnamed protein product; Similar to putative membrane protein YegM of Escherichia coli; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.597
macA	plu0759	plu1590	plu0759	Macrolide-specific efflux protein MacA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	HlyD_D23 domain-containing protein; Unnamed protein product; Some similarities with multidrug efflux membrane fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.678
macA	plu2734	plu1590	plu2734	Macrolide-specific efflux protein MacA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	HlyD_D23 domain-containing protein; Unnamed protein product; Membrane fusion protein (MPF) component of efflux system; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.635
macA	plu2735	plu1590	plu2735	Macrolide-specific efflux protein MacA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Unnamed protein product; Similar to ABC transporter (ATP-binding protein subunit).	0.456
macA	plu2736	plu1590	plu2736	Macrolide-specific efflux protein MacA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Unnamed protein product; Similar to ABC transporter (permease subunit).	0.839
macB	acrA	plu1591	plu3851	Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	Acriflavin resistance protein A precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.839
macB	bvgS	plu1591	plu2284	Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	Virulence sensor protein BvgS precursor.	0.710
macB	hslJ	plu1591	plu2144	Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	Heat shock protein HslJ.	0.691
macB	macA	plu1591	plu1590	Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	Macrolide-specific efflux protein MacA precursor; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.959
macB	mdtA	plu1591	plu2774	Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	Multidrug resistance protein MdtA; Unnamed protein product; Similar to putative membrane protein YegM of Escherichia coli; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.806
macB	plu0759	plu1591	plu0759	Macrolide-specific ABC-type efflux carrier protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	HlyD_D23 domain-containing protein; Unnamed protein product; Some similarities with multidrug efflux membrane fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.806

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