lrp protein (Photorhabdus laumondii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

lrp

Leucine-responsive regulatory protein. (164 aa)

Predicted Functional Partners:

lrhA

0.839

leuO

0.709

hfq

0.686

proQ

0.625

fliZ

0.623

phlB

0.597

pdl

0.597

ftsK

0.541

phlA

0.539

hsdR

0.539

Your Current Organism:

Photorhabdus laumondii

NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
fliZ	hfq	plu1956	plu4581	FliZ protein.	Host factor-I protein (HF-I) (HF-1); RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.	0.534
fliZ	hsdR	plu1956	plu4322	FliZ protein.	Type I site-specific deoxyribonuclease HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification.	0.620
fliZ	leuO	plu1956	plu3672	FliZ protein.	Activator protein in leuABCD operon; Belongs to the LysR transcriptional regulatory family.	0.623
fliZ	lrp	plu1956	plu1600	FliZ protein.	Leucine-responsive regulatory protein.	0.623
ftsK	lrp	plu1601	plu1600	Cell division protein.	Leucine-responsive regulatory protein.	0.541
hfq	fliZ	plu4581	plu1956	Host factor-I protein (HF-I) (HF-1); RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.	FliZ protein.	0.534
hfq	hsdR	plu4581	plu4322	Host factor-I protein (HF-I) (HF-1); RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.	Type I site-specific deoxyribonuclease HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification.	0.538
hfq	leuO	plu4581	plu3672	Host factor-I protein (HF-I) (HF-1); RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.	Activator protein in leuABCD operon; Belongs to the LysR transcriptional regulatory family.	0.813
hfq	lrp	plu4581	plu1600	Host factor-I protein (HF-I) (HF-1); RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.	Leucine-responsive regulatory protein.	0.686
hfq	proQ	plu4581	plu2683	Host factor-I protein (HF-I) (HF-1); RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.	ProP effector; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family.	0.530
hsdR	fliZ	plu4322	plu1956	Type I site-specific deoxyribonuclease HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification.	FliZ protein.	0.620
hsdR	hfq	plu4322	plu4581	Type I site-specific deoxyribonuclease HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification.	Host factor-I protein (HF-I) (HF-1); RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.	0.538
hsdR	leuO	plu4322	plu3672	Type I site-specific deoxyribonuclease HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification.	Activator protein in leuABCD operon; Belongs to the LysR transcriptional regulatory family.	0.539
hsdR	lrp	plu4322	plu1600	Type I site-specific deoxyribonuclease HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification.	Leucine-responsive regulatory protein.	0.539
leuO	fliZ	plu3672	plu1956	Activator protein in leuABCD operon; Belongs to the LysR transcriptional regulatory family.	FliZ protein.	0.623
leuO	hfq	plu3672	plu4581	Activator protein in leuABCD operon; Belongs to the LysR transcriptional regulatory family.	Host factor-I protein (HF-I) (HF-1); RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.	0.813
leuO	hsdR	plu3672	plu4322	Activator protein in leuABCD operon; Belongs to the LysR transcriptional regulatory family.	Type I site-specific deoxyribonuclease HsdR; Subunit R is required for both nuclease and ATPase activities, but not for modification.	0.539
leuO	lrp	plu3672	plu1600	Activator protein in leuABCD operon; Belongs to the LysR transcriptional regulatory family.	Leucine-responsive regulatory protein.	0.709
leuO	proQ	plu3672	plu2683	Activator protein in leuABCD operon; Belongs to the LysR transcriptional regulatory family.	ProP effector; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family.	0.566
lrhA	lrp	plu3090	plu1600	LrhA (HexA) may be a general repressor of primary-specific phenotype. lrhA expression is increased (at least 10-fold) in the secondary variant of K122, UK210 and TT01; Belongs to the LysR transcriptional regulatory family.	Leucine-responsive regulatory protein.	0.839

page 1 of 3

Server load: medium (48%) [HD]

Permalink

Network

Neighborhood

Experiments

Co-occurrence

Textmining

Co-expression

Databases

Fusion

© STRING Consortium 2026

Credits

Access

Info

About