| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cysG | lolA | plu0708 | plu1602 | Sirohaem synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Outer-membrane lipoproteins carrier protein precursor (P20); Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | 0.471 |
| cysG | plu1603 | plu0708 | plu1603 | Sirohaem synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | AAA domain-containing protein; Unnamed protein product; Similar to putative polynucleotide enzyme YcaJ of Escherichia coli. | 0.440 |
| dnaN | plu1603 | plu0002 | plu1603 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | AAA domain-containing protein; Unnamed protein product; Similar to putative polynucleotide enzyme YcaJ of Escherichia coli. | 0.719 |
| dnaN | plu4452 | plu0002 | plu4452 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | Unnamed protein product; Similar to ATP-dependent DNA helicase. | 0.668 |
| dnaN | recQ | plu0002 | plu4620 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | ATP-dependent DNA helicase RecQ. | 0.586 |
| dusC | plu1603 | plu1512 | plu1603 | tRNA-dihydrouridine(16) synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. | AAA domain-containing protein; Unnamed protein product; Similar to putative polynucleotide enzyme YcaJ of Escherichia coli. | 0.451 |
| ftsK | lolA | plu1601 | plu1602 | Cell division protein. | Outer-membrane lipoproteins carrier protein precursor (P20); Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | 0.840 |
| ftsK | plu1603 | plu1601 | plu1603 | Cell division protein. | AAA domain-containing protein; Unnamed protein product; Similar to putative polynucleotide enzyme YcaJ of Escherichia coli. | 0.618 |
| ftsK | serS | plu1601 | plu1604 | Cell division protein. | seryl-tRNA synthetase (serine--tRNA ligase) (SERRS); Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.475 |
| lolA | cysG | plu1602 | plu0708 | Outer-membrane lipoproteins carrier protein precursor (P20); Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | Sirohaem synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.471 |
| lolA | ftsK | plu1602 | plu1601 | Outer-membrane lipoproteins carrier protein precursor (P20); Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | Cell division protein. | 0.840 |
| lolA | plu1603 | plu1602 | plu1603 | Outer-membrane lipoproteins carrier protein precursor (P20); Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | AAA domain-containing protein; Unnamed protein product; Similar to putative polynucleotide enzyme YcaJ of Escherichia coli. | 0.860 |
| lolA | serS | plu1602 | plu1604 | Outer-membrane lipoproteins carrier protein precursor (P20); Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | seryl-tRNA synthetase (serine--tRNA ligase) (SERRS); Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.709 |
| nadE | plu1603 | plu3310 | plu1603 | NH(3)-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | AAA domain-containing protein; Unnamed protein product; Similar to putative polynucleotide enzyme YcaJ of Escherichia coli. | 0.631 |
| nuoC | plu1603 | plu3087 | plu1603 | NADH dehydrogenase I chain C/D (NADH-ubiquinone oxidoreductase chain 3/4) (NUO3/NUO4); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | AAA domain-containing protein; Unnamed protein product; Similar to putative polynucleotide enzyme YcaJ of Escherichia coli. | 0.476 |
| nuoC | plu4452 | plu3087 | plu4452 | NADH dehydrogenase I chain C/D (NADH-ubiquinone oxidoreductase chain 3/4) (NUO3/NUO4); NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | Unnamed protein product; Similar to ATP-dependent DNA helicase. | 0.451 |
| plu1603 | cysG | plu1603 | plu0708 | AAA domain-containing protein; Unnamed protein product; Similar to putative polynucleotide enzyme YcaJ of Escherichia coli. | Sirohaem synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.440 |
| plu1603 | dnaN | plu1603 | plu0002 | AAA domain-containing protein; Unnamed protein product; Similar to putative polynucleotide enzyme YcaJ of Escherichia coli. | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | 0.719 |
| plu1603 | dusC | plu1603 | plu1512 | AAA domain-containing protein; Unnamed protein product; Similar to putative polynucleotide enzyme YcaJ of Escherichia coli. | tRNA-dihydrouridine(16) synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs. Belongs to the Dus family. DusC subfamily. | 0.451 |
| plu1603 | ftsK | plu1603 | plu1601 | AAA domain-containing protein; Unnamed protein product; Similar to putative polynucleotide enzyme YcaJ of Escherichia coli. | Cell division protein. | 0.618 |
