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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pflBFormate acetyltransferase I (pyruvate formate-lyase 1). (760 aa)    
Predicted Functional Partners:
pflA
Pyruvate formate-lyase 1 activating enzyme (PFL-activating enzyme); Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.
  
 0.992
adhE
Aldehyde-alcohol dehydrogenase [includes: alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase [acetylating] (ACDH); pyruvate-formate-lyase deactivase (PFL deactivase)]; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
 
 0.978
plu1883
Transket_pyr domain-containing protein; Unnamed protein product; Similar to 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) alpha/beta E1 chain CP0743.
   
 
 0.963
plu2795
Transket_pyr domain-containing protein; Unnamed protein product; Similar to 3-methyl-2-oxobutanoate dehydrogenase (lipoamide). Putative transmembrane protein.
   
 
 0.963
maeB
NADP-dependent malic enzyme (NADP-ME).
  
 
 0.947
pta
Phosphate acetyltransferase (phosphotransacetylase); Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.943
maeA
Malate dehydrogenase (oxaloacetate-decarboxylating); Belongs to the malic enzymes family.
   
 
 0.925
ldhA
D-lactate dehydrogenase (D-LDH); Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
     
 0.919
pykA
Pyruvate kinase II; Belongs to the pyruvate kinase family.
   
 
 0.916
pykF
Pyruvate kinase I (PK-1); Belongs to the pyruvate kinase family.
   
 
 0.916
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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