Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
plu1749Lactamase_B domain-containing protein; Unnamed protein product; Highly similar to probable hydrolase YcbL of Escherichia coli. (215 aa)    
Predicted Functional Partners:
gloA
Lactoylglutathione lyase (methylglyoxalase) (S-D-lactolyglutathione methylglyoxal lyase); Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
  
 0.937
gloB
Hydroxyacylglutathione hydrolase (glyoxalase II); Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
  
  
0.912
dld
D-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family.
  
  
  0.912
plu1748
Uncharacterized protein; Truncated gene. Similar to C-terminal part of putative amidase YcbB precursor of Escherichia coli.
  
    0.908
ldhA
D-lactate dehydrogenase (D-LDH); Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.905
plu2238
Lactamase_B domain-containing protein; Unnamed protein product; Highly similar to Zn-dependent hydrolases and to AHL-lactonase.
      
 0.623
plu2016
Unnamed protein product; Weakly similar to transcriptional regulator, LuxR family.
    
 
 0.584
plu3729
PAS_4 domain-containing protein; Unnamed protein product; Some similarities with transcription regulator LuxR family.
    
 
 0.584
plu3735
PAS_4 domain-containing protein; Unnamed protein product; Some similarities with LuxR family transcriptional regulator.
    
 
 0.584
plu0925
HTH luxR-type domain-containing protein; Unnamed protein product; Weakly similar to transcriptional regulator, LuxR family.
    
 
 0.582
Your Current Organism:
Photorhabdus laumondii
NCBI taxonomy Id: 243265
Other names: P. laumondii subsp. laumondii TTO1, Photorhabdus laumondii subsp. laumondii TTO1, Photorhabdus luminescens subsp. laumondii TTO1
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